Literature DB >> 33025079

Experiences with the Kono-S anastomosis in Crohn's disease of the terminal ileum-a cohort study.

K Horisberger1, D L Birrer2, A Rickenbacher2, M Turina2.   

Abstract

PURPOSE: The most frequent long-term complication after ileocecal resection in Crohn's disease is anastomotic recurrence and subsequent stenosis. Recurrence typically begins at the site of the anastomosis, raising the question of whether the surgical technique of the anastomosis could affect recurrence rates. Kono-S anastomosis is a hand-sewn antimesenteric functional end-to-end anastomosis that offers a wide lumen that is well accessible for endoscopic dilatation. The purpose of our study is to review the rate of postoperative complications almost 2 years after the introduction of this technique.
MATERIALS AND METHODS: This is a prospective single-center cohort study of all consecutive patients with Crohn's disease undergoing ileocecal resection. Patients' characteristics as well as specific data for the surgical procedure and short-term outcome were evaluated.
RESULTS: Thirty patients were operated for Crohn's disease of the terminal ileum (n = 24) or anastomotic recurrence (n = 6). Postoperative complications with a Clavien-Dindo Score ≥ IIIb were observed in three patients. One patient showed a hemorrhage and underwent surgical hemostasis. Two patients developed anastomotic leakage; in both cases, ileostomy was created after resection of the anastomosis. The median hospital stay was 9 days (IQR 7-12). A comparison with a historic group of conventionally operated patients of our hospital revealed no differences in short-term results except for the duration of surgery.
CONCLUSION: The Kono-S anastomosis is associated with acceptable short-term results, complications, and recurrence rates comparable with the established anastomotic techniques. Longer operation times are observed, but the few published studies concerning long-term recurrence are promising.

Entities:  

Keywords:  Crohn’s disease; Ileocecal resection; Kono-S anastomosis; Terminal ileum

Year:  2020        PMID: 33025079     DOI: 10.1007/s00423-020-01998-6

Source DB:  PubMed          Journal:  Langenbecks Arch Surg        ISSN: 1435-2443            Impact factor:   3.445


  30 in total

Review 1.  Review article: the natural history of postoperative Crohn's disease recurrence.

Authors:  A Buisson; J-B Chevaux; P B Allen; G Bommelaer; L Peyrin-Biroulet
Journal:  Aliment Pharmacol Ther       Date:  2012-02-07       Impact factor: 8.171

2.  Infliximab prevents Crohn's disease recurrence after ileal resection.

Authors:  Miguel Regueiro; Wolfgang Schraut; Leonard Baidoo; Kevin E Kip; Antonia R Sepulveda; Marilyn Pesci; Janet Harrison; Scott E Plevy
Journal:  Gastroenterology       Date:  2008-10-31       Impact factor: 22.682

Review 3.  Timing of surgery in Crohn's disease: a key issue in the management.

Authors:  Rafael Alós; Joaquín Hinojosa
Journal:  World J Gastroenterol       Date:  2008-09-28       Impact factor: 5.742

4.  Factors influencing disease recurrence after ileocolic resection in adult and pediatric onset Crohn's disease.

Authors:  Iuliana D Bobanga; Shiyu Bai; Marco A Swanson; Bradley J Champagne; Harry J Reynolds; Conor P Delaney; Edward M Barksdale; Sharon L Stein
Journal:  Am J Surg       Date:  2014-07-18       Impact factor: 2.565

5.  Laparoscopic ileocaecal resection versus infliximab for terminal ileitis in Crohn's disease: a randomised controlled, open-label, multicentre trial.

Authors:  Cyriel Y Ponsioen; E Joline de Groof; Emma J Eshuis; Tjibbe J Gardenbroek; Patrick M M Bossuyt; Ailsa Hart; Janindra Warusavitarne; Christianne J Buskens; Ad A van Bodegraven; Menno A Brink; Esther C J Consten; Bart A van Wagensveld; Marno C M Rijk; Rogier M P H Crolla; Casper G Noomen; Alexander P J Houdijk; Rosalie C Mallant; Maarten Boom; Willem A Marsman; Hein B Stockmann; Bregje Mol; A Jeroen de Groof; Pieter C Stokkers; Geert R D'Haens; Willem A Bemelman
Journal:  Lancet Gastroenterol Hepatol       Date:  2017-08-31

6.  A new antimesenteric functional end-to-end handsewn anastomosis: surgical prevention of anastomotic recurrence in Crohn's disease.

Authors:  Toru Kono; Toshifumi Ashida; Yoshiaki Ebisawa; Naoyuki Chisato; Kotaro Okamoto; Hidetoshi Katsuno; Kotaro Maeda; Mikihiro Fujiya; Yutaka Kohgo; Hiroyuki Furukawa
Journal:  Dis Colon Rectum       Date:  2011-05       Impact factor: 4.585

Review 7.  Postoperative Crohn's disease recurrence: a practical approach.

Authors:  Pilar Nos; Eugeni Domenech
Journal:  World J Gastroenterol       Date:  2008-09-28       Impact factor: 5.742

Review 8.  Management and prevention of postoperative Crohn's disease.

Authors:  Miguel Regueiro
Journal:  Inflamm Bowel Dis       Date:  2009-10       Impact factor: 5.325

9.  Ten years of infliximab for Crohn's disease: outcome in 469 patients from 2 tertiary referral centers.

Authors:  Emma J Eshuis; Charlotte P Peters; Adriaan A van Bodegraven; Joep F Bartelsman; Willem Bemelman; Paul Fockens; Geert R A M D'Haens; Pieter C F Stokkers; Cyriel Y Ponsioen
Journal:  Inflamm Bowel Dis       Date:  2013-07       Impact factor: 5.325

10.  Inclusion of the Mesentery in Ileocolic Resection for Crohn's Disease is Associated With Reduced Surgical Recurrence.

Authors:  Calvin J Coffey; Miranda G Kiernan; Shaheel M Sahebally; Awad Jarrar; John P Burke; Patrick A Kiely; Bo Shen; David Waldron; Colin Peirce; Manus Moloney; Maeve Skelly; Paul Tibbitts; Hena Hidayat; Peter N Faul; Vourneen Healy; Peter D O'Leary; Leon G Walsh; Peter Dockery; Ronan P O'Connell; Sean T Martin; Fergus Shanahan; Claudio Fiocchi; Colum P Dunne
Journal:  J Crohns Colitis       Date:  2018-11-09       Impact factor: 9.071

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  2 in total

Review 1.  Surgical Strategies to Reduce Postoperative Recurrence of Crohn's Disease After Ileocolic Resection.

Authors:  Ian S Reynolds; Katie L Doogan; Éanna J Ryan; Daniel Hechtl; Frederik P Lecot; Shobhit Arya; Sean T Martin
Journal:  Front Surg       Date:  2021-12-17

Review 2.  Surgical Management of Small Bowel Crohn's Disease.

Authors:  Pramodh Chandrasinghe
Journal:  Front Surg       Date:  2022-04-15
  2 in total

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