Literature DB >> 33023444

Herbal Medicine in the Treatment of Epilepsy.

Simin Namvar Aghdash1.   

Abstract

Epilepsy is one of the most common disorders of the central nervous system. Although epilepsy is common worldwide, approximately 80% of epileptic patients live in the developing countries or those with low-middle income. Up until the second decade of the 20th century, epilepsy was treated mostly by traditional remedies. Today, antiepileptic drugs are used as a general treatment instead to prevent and control epileptic seizures. However, patient access to these drugs is hindered due to the healthcare systems of their countries and a number of other reasons, such as cultural, socio-demographic, and financial poverty. In addition, approximately 30-40%of epileptic patients suffer from refractory epilepsy, additionally, AEDs have adverse side-effects that can lead to treatment failure or reduce the patient's quality of life. Despite recent advances in the treatment of epilepsy, there is still a need for improving medical treatment with a particular focus on efficacy, safety, and accessibility. Since herbal medicines have been used for many centuries around the world for treating epilepsy, it is, therefore, plausible that a rigorous study on herbal medicine and phytochemical components within plants of various species and origin may lead to the discovery of novel AEDs. Nowadays, many medicinal plants used in different cultures and regions of the world have been identified. Most phytochemical components of these plants have been identified and, in some cases, their targets located. Therefore, it is possible that new, effective, and accessible anticonvulsants drugs can be obtained from a medicinal plant. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Entities:  

Keywords:  Epilepsy; antiepileptic drugs; herbal medicine; kindling; phytochemicals; seizures

Year:  2021        PMID: 33023444     DOI: 10.2174/1389450121999201001152221

Source DB:  PubMed          Journal:  Curr Drug Targets        ISSN: 1389-4501            Impact factor:   3.465


  2 in total

Review 1.  Therapeutic Potential of Quercetin and its Derivatives in Epilepsy: Evidence from Preclinical Studies.

Authors:  Chandra Prakash; Jyoti Tyagi; Shyam Sunder Rabidas; Vijay Kumar; Deepak Sharma
Journal:  Neuromolecular Med       Date:  2022-08-11       Impact factor: 4.103

Review 2.  Neuroprotective effects of carvacrol against Alzheimer's disease and other neurodegenerative diseases: A review.

Authors:  Zahra Azizi; Nahid Majlessi; Samira Choopani; Nasser Naghdi
Journal:  Avicenna J Phytomed       Date:  2022 Jul-Aug
  2 in total

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