PURPOSE: To describe a case of inflammatory chorioretinopathy and Adie's syndrome possibly associated with COVID-19. METHODS: Observational case report. RESULTS: A 51-year-old woman developed fever, cough, and headache followed by retro-ocular pain and reading impairment. She tested positive for SARS-COV-2 infection by qualitative real-time reverse-transcriptase-polymerase-chain-reaction. The slit-lamp and funduscopic exam revealed abnormal pupillary response and yellowish creamy deep chorioretinal lesions, which were not present in previous examinations. Instillation of pilocarpine demonstrated denervation supersensitivity, and it was suggestive of bilateral Adie tonic pupil. A comprehensive work-up ruled out other systemic, autoimmune, or infectious diseases. CONCLUSIONS: This case illustrates the possible association between multifocal chorioretinitis and Adie's syndrome, and the SARS-COV-2 infection in humans. Further investigation of virus infectivity specifically within ocular tissues has to be conducted.
PURPOSE: To describe a case of inflammatory chorioretinopathy and Adie's syndrome possibly associated with COVID-19. METHODS: Observational case report. RESULTS: A 51-year-old woman developed fever, cough, and headache followed by retro-ocular pain and reading impairment. She tested positive for SARS-COV-2 infection by qualitative real-time reverse-transcriptase-polymerase-chain-reaction. The slit-lamp and funduscopic exam revealed abnormal pupillary response and yellowish creamy deep chorioretinal lesions, which were not present in previous examinations. Instillation of pilocarpine demonstrated denervation supersensitivity, and it was suggestive of bilateral Adie tonic pupil. A comprehensive work-up ruled out other systemic, autoimmune, or infectious diseases. CONCLUSIONS: This case illustrates the possible association between multifocal chorioretinitis and Adie's syndrome, and the SARS-COV-2 infection in humans. Further investigation of virus infectivity specifically within ocular tissues has to be conducted.
Authors: Timothy P H Lin; Chung-Nga Ko; Ke Zheng; Kenny H W Lai; Raymond L M Wong; Allie Lee; Shaochong Zhang; Suber S Huang; Kelvin H Wan; Dennis S C Lam Journal: Asia Pac J Ophthalmol (Phila) Date: 2021-11-24
Authors: Josef Penkava; Maximilian Muenchhoff; Irina Badell; Andreas Osterman; Claire Delbridge; Florian Niederbuchner; Sarah Soliman; Martina Rudelius; Alexander Graf; Stefan Krebs; Helmut Blum; Michael Ulbig; Carmen Baumann; Daniel Zapp; Mathias Maier; Oliver T Keppler; Chris P Lohmann; Stephan Ledderose Journal: Graefes Arch Clin Exp Ophthalmol Date: 2021-12-28 Impact factor: 3.117