Literature DB >> 33021386

Circular RNA as a potential diagnostic and/or therapeutic target for endometriosis.

Parisa M Dana1, Mona Taghavipour2, Hamed Mirzaei1, Bahman Yousefi3,4, Bahram Moazzami5, Shahla Chaichian5, Zatollah Asemi1.   

Abstract

Endometriosis is a pathology form of endometrium that behaves in a similar way to malignancies, such as invasion and resistance to apoptosis. Circular RNAs (CircRNAs) are a class of noncoding RNAs that have several biological functions including, miRNA sponging, sequestering of proteins, enhancing parental gene expression and translation resulting in polypeptides. In this review, we highlighted the roles of circRNAs as potential diagnostic and therapeutic biomarkers in endometriosis. Moreover, we summarized the roles of circRNAs in the pathogenesis of endometriosis via different signaling pathways, such as the miRNA network and apoptosis.

Entities:  

Keywords:  circRNA; endometriosis; miRNA; signaling pathway

Year:  2020        PMID: 33021386     DOI: 10.2217/bmm-2020-0167

Source DB:  PubMed          Journal:  Biomark Med        ISSN: 1752-0363            Impact factor:   2.851


  2 in total

1.  Circular RNA PIP5K1A (circPIP5K1A) accelerates endometriosis progression by regulating the miR-153-3p/Thymosin Beta-4 X-Linked (TMSB4X) pathway.

Authors:  Lin Sun; Yan Wei; Junli Wang
Journal:  Bioengineered       Date:  2021-12       Impact factor: 3.269

2.  Downregulation of circ_0000673 Promotes Cell Proliferation and Migration in Endometriosis via the Mir-616-3p/PTEN Axis.

Authors:  Yongwen Yang; Deying Ban; Chun Zhang; Licong Shen
Journal:  Int J Med Sci       Date:  2021-08-17       Impact factor: 3.738

  2 in total

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