Literature DB >> 3301783

Treatment of bacillary dysentery: a comparison between enoxacin and nalidixic acid.

P De Mol, T Mets, R Lagasse, J Vandepitte, A Mutwewingabo, J P Butzler.   

Abstract

A prospective randomized study has been conducted in Rwanda to compare the efficacy of enoxacin versus nalidixic acid for the treatment of bacillary dysentery in adults. Seventeen patients received nalidixic acid and 21 received enoxacin. All isolates (37 shigella, 1 campylobacter) were sensitive in vitro to the two drugs. All patients showed a favourable clinical and bacteriological response and the results obtained with both drugs were comparable. Enoxacin seems to be a good alternative to nalidixic acid for bacillary dysentery due to multiresistant shigella.

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Year:  1987        PMID： 3301783     DOI： 10.1093/jac/19.5.695

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN： 0305-7453            Impact factor:   5.790


  10 in total

Review 1.  Antibiotic therapy for Shigella dysentery.

Authors:  Prince Rh Christopher; Kirubah V David; Sushil M John; Venkatesan Sankarapandian
Journal:  Cochrane Database Syst Rev       Date:  2010-08-04

Review 2.  Enoxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Authors:  J M Henwood; J P Monk
Journal:  Drugs       Date:  1988-07       Impact factor: 9.546

Review 3.  Enoxacin: a reappraisal of its clinical efficacy in the treatment of genitourinary tract infections.

Authors:  S S Patel; C M Spencer
Journal:  Drugs       Date:  1996-01       Impact factor: 9.546

4.  In vitro antimicrobial susceptibility testing of bacterial enteropathogens causing traveler's diarrhea in four geographic regions.

Authors:  H Gomi; Z D Jiang; J A Adachi; D Ashley; B Lowe; M P Verenkar; R Steffen; H L DuPont
Journal:  Antimicrob Agents Chemother       Date:  2001-01       Impact factor: 5.191

5.  Antimicrobial resistance of Shigella isolates causing traveler's diarrhea.

Authors:  J Vila; J Gascon; S Abdalla; J Gomez; F Marco; A Moreno; M Corachan; T Jimenez de Anta
Journal:  Antimicrob Agents Chemother       Date:  1994-11       Impact factor: 5.191

Review 6.  Quinolones in the treatment of acute bacterial diarrhoeal diseases.

Authors:  H E Akalin
Journal:  Drugs       Date:  1993       Impact factor: 9.546

Review 7.  The new quinolones in the treatment of diarrhoea and typhoid fever.

Authors:  A Waiz
Journal:  Drugs       Date:  1995       Impact factor: 9.546

Review 8.  Quinolones and the gastrointestinal tract.

Authors:  B E Murray
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1989-12       Impact factor: 3.267

Review 9.  Fluoroquinolone antimicrobial agents.

Authors:  J S Wolfson; D C Hooper
Journal:  Clin Microbiol Rev       Date:  1989-10       Impact factor: 26.132

Review 10.  Clinical overview of enoxacin.

Authors:  S H Zinner
Journal:  Clin Pharmacokinet       Date:  1989       Impact factor: 6.447
  10 in total

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