Nicole Marsh1,2,3, Joan Webster1,2, Amanda J Ullman1,2,3, Gabor Mihala2,4,5, Marie Cooke2,3, Vineet Chopra2,6, Claire M Rickard1,2,3. 1. Nursing and Midwifery Research Centre, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia. 2. Alliance for Vascular Access Teaching and Research, Menzies Health Institute Queensland, Griffith University, Brisbane, Queensland, Australia. 3. School of Nursing and Midwifery, Griffith University, Brisbane, Australia. 4. School of Medicine, Griffith University, Brisbane, Queensland, Australia. 5. Centre for Applied Health Economics, Menzies Health Institute Queensland, Griffith University, Brisbane, Queensland, Australia. 6. Division of Hospital Medicine, Department of Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Abstract
AIMS: The aim of this systematic review and meta-analysis was to summarize and quantify peripheral intravenous catheter-related complications. DESIGN: This systematic review is reported by means of the Cochrane process for randomized controlled trials and the Meta-analysis of Observation Studies in Epidemiology for cohort studies. DATA SOURCES: The Cochrane Central Register of Controlled Trials, PubMed, CINAHL and EMBASE databases, clinical trial registries such as ClinicalTrials.gov and the reference list of included studies were searched from 2000 -April 2019. REVIEW METHODS: Using a purpose designed data extraction tool, two authors independently identified studies for full review, data extraction and quality assessment. Dichotomous outcomes were pooled after Freeman-Tukey double arcsine transformation using random-effects meta-analysis; estimates of heterogeneity were taken from inverse-variance fixed-effect models. RESULTS: Seventy observational studies and 33 randomized controlled trials were included (76,977 catheters). Peripheral intravenous catheter-related complications were as follows: phlebitis (with definition) 19.3%, phlebitis (without definition) 4.5%, infiltration/extravasation 13.7%, occlusion 8%, leakage 7.3%, pain 6.4% and dislodgement 6.0%. Subgroup analysis found infiltration/extravasation for emergency department-inserted catheters was significantly higher (25.2%; p = .022) than for those inserted in other departments and pain was significantly higher (p < .001) in countries with developing economies compared with developed economies. CONCLUSION: Peripheral intravenous catheter complications are unacceptably common worldwide. This review suggests substantial and multi-specialty efforts are needed to address the sequalae associated with complications. The potential benefits for patients and health services are considerable if complications are reduced. IMPACT: Peripheral intravenous complications interrupt important treatment which can be distressing for patients and result in longer hospital stays with increased healthcare costs. This review found phlebitis and infiltration are the most prevalent reason for catheter failure. These results provide nurses with a strong evidence base for the development of effective interventions for practice which are vital for preventing poor outcomes for patients with peripheral intravenous catheters.
AIMS: The aim of this systematic review and meta-analysis was to summarize and quantify peripheral intravenous catheter-related complications. DESIGN: This systematic review is reported by means of the Cochrane process for randomized controlled trials and the Meta-analysis of Observation Studies in Epidemiology for cohort studies. DATA SOURCES: The Cochrane Central Register of Controlled Trials, PubMed, CINAHL and EMBASE databases, clinical trial registries such as ClinicalTrials.gov and the reference list of included studies were searched from 2000 -April 2019. REVIEW METHODS: Using a purpose designed data extraction tool, two authors independently identified studies for full review, data extraction and quality assessment. Dichotomous outcomes were pooled after Freeman-Tukey double arcsine transformation using random-effects meta-analysis; estimates of heterogeneity were taken from inverse-variance fixed-effect models. RESULTS: Seventy observational studies and 33 randomized controlled trials were included (76,977 catheters). Peripheral intravenous catheter-related complications were as follows: phlebitis (with definition) 19.3%, phlebitis (without definition) 4.5%, infiltration/extravasation 13.7%, occlusion 8%, leakage 7.3%, pain 6.4% and dislodgement 6.0%. Subgroup analysis found infiltration/extravasation for emergency department-inserted catheters was significantly higher (25.2%; p = .022) than for those inserted in other departments and pain was significantly higher (p < .001) in countries with developing economies compared with developed economies. CONCLUSION: Peripheral intravenous catheter complications are unacceptably common worldwide. This review suggests substantial and multi-specialty efforts are needed to address the sequalae associated with complications. The potential benefits for patients and health services are considerable if complications are reduced. IMPACT: Peripheral intravenous complications interrupt important treatment which can be distressing for patients and result in longer hospital stays with increased healthcare costs. This review found phlebitis and infiltration are the most prevalent reason for catheter failure. These results provide nurses with a strong evidence base for the development of effective interventions for practice which are vital for preventing poor outcomes for patients with peripheral intravenous catheters.
Authors: Paulo Santos-Costa; Filipe Paiva-Santos; Liliana B Sousa; Rafael A Bernardes; Filipa Ventura; William David Fearnley; Anabela Salgueiro-Oliveira; Pedro Parreira; Margarida Vieira; João Graveto Journal: J Pers Med Date: 2022-01-24
Authors: Fabiana Bolela; Roberta de Lima; Ana Carolina de Souza; Michele Rocha Moreira; Ana Julia de Oliveira Lago; Giovana Paula Rezende Simino; Jakeline Silva de Araújo Journal: Rev Lat Am Enfermagem Date: 2022
Authors: Paulo Santos-Costa; Filipe Paiva-Santos; Liliana B Sousa; Rafael A Bernardes; Filipa Ventura; Anabela Salgueiro-Oliveira; Pedro Parreira; Margarida Vieira; João Graveto Journal: Nurs Rep Date: 2022-07-07
Authors: Paulo Santos-Costa; Mariana Alves; Carolina Sousa; Liliana B Sousa; Filipe Paiva-Santos; Rafael A Bernardes; Filipa Ventura; Anabela Salgueiro-Oliveira; Pedro Parreira; Margarida Vieira; João Graveto Journal: Int J Environ Res Public Health Date: 2022-09-05 Impact factor: 4.614