Literature DB >> 3301170

Free drug monitoring.

S Chan, B Gerson.   

Abstract

The principles, technique of measurement, and clinical significance of free drugs are reviewed. Albumin, alpha-1-acid glycoprotein, and lipoprotein are the main drug-binding proteins in blood. Variations of the concentrations of these proteins owing to disease would result in changes in the free drug levels. These levels may be determined by equilibrium dialysis, ultrafiltration, and other techniques.

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Substances:

Year:  1987        PMID: 3301170

Source DB:  PubMed          Journal:  Clin Lab Med        ISSN: 0272-2712            Impact factor:   1.935


  11 in total

Review 1.  Antiretroviral drug concentrations in semen of HIV-1 infected men.

Authors:  S Taylor; A S Pereira
Journal:  Sex Transm Infect       Date:  2001-02       Impact factor: 3.519

2.  Targeted nanogels: a versatile platform for drug delivery to tumors.

Authors:  Eric A Murphy; Bharat K Majeti; Rajesh Mukthavaram; Lisette M Acevedo; Leo A Barnes; David A Cheresh
Journal:  Mol Cancer Ther       Date:  2011-04-25       Impact factor: 6.261

3.  Characterization of solution-phase drug-protein interactions by ultrafast affinity extraction.

Authors:  Sandya R Beeram; Xiwei Zheng; Kyungah Suh; David S Hage
Journal:  Methods       Date:  2018-03-03       Impact factor: 3.608

4.  Irreversible binding of an anticancer compound (BI-94) to plasma proteins.

Authors:  Nagsen Gautam; Rhishikesh Thakare; Sandeep Rana; Amarnath Natarajan; Yazen Alnouti
Journal:  Xenobiotica       Date:  2015-04-14       Impact factor: 1.908

Review 5.  Characterization of drug interactions with serum proteins by using high-performance affinity chromatography.

Authors:  David S Hage; Jeanethe Anguizola; Omar Barnaby; Abby Jackson; Michelle J Yoo; Efthimia Papastavros; Erika Pfaunmiller; Matt Sobansky; Zenghan Tong
Journal:  Curr Drug Metab       Date:  2011-05       Impact factor: 3.731

6.  Population analysis of a 24-h paclitaxel infusion in advanced endometrial cancer: a gynaecological oncology group study.

Authors:  Diane R Mould; Gini F Fleming; Kathleen M Darcy; David Spriggs
Journal:  Br J Clin Pharmacol       Date:  2006-07       Impact factor: 4.335

Review 7.  Analysis of biomolecular interactions using affinity microcolumns: a review.

Authors:  Xiwei Zheng; Zhao Li; Sandya Beeram; Maria Podariu; Ryan Matsuda; Erika L Pfaunmiller; Christopher J White; NaTasha Carter; David S Hage
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2014-01-27       Impact factor: 3.205

Review 8.  Characterization of drug-protein interactions in blood using high-performance affinity chromatography.

Authors:  David S Hage; Abby Jackson; Matthew R Sobansky; John E Schiel; Michelle J Yoo; K S Joseph
Journal:  J Sep Sci       Date:  2009-03       Impact factor: 3.645

Review 9.  Selected pharmacokinetic issues of the use of antiepileptic drugs and parenteral nutrition in critically ill patients.

Authors:  Muhannad R M Salih; Mohd Baidi Bahari; Arwa Y Abd
Journal:  Nutr J       Date:  2010-12-31       Impact factor: 3.271

10.  Impact of Serum Proteins on the Uptake and RNAi Activity of GalNAc-Conjugated siRNAs.

Authors:  Saket Agarwal; Ruth Allard; Justin Darcy; Samantha Chigas; Yongli Gu; Tuyen Nguyen; Sarah Bond; Saeho Chong; Jing-Tao Wu; Maja M Janas
Journal:  Nucleic Acid Ther       Date:  2021-04-15       Impact factor: 5.486

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