Literature DB >> 33010136

Effect of receiver shape and volume on the Alzheimer disease for molecular communication via diffusion.

Ibrahim Isik1, H Birkan Yilmaz2, Ilker Demirkol3, Mehmet Emin Tagluk4.   

Abstract

Nano-devices are featured to communicate via molecular interaction, the so-called molecular communication (MC). In MC systems, the information is carried by molecules where the amount of molecules constitutes the level of the signal. In this study, an MC-based system was analysed with different receiver topology and related parameters, such as size, shape, and orientation of receptors on the receiver. Also in the concept of nano-medicine, the effect of amyloid-beta ([inline-formula removed]), which is believed as the main cause of Alzheimer disease, on the successful reception ratio of molecules with the proposed receiver models was investigated. It was demonstrated that the cubic receiver model is superior to sphere one in terms of the correct reception ratio of the molecular signal. A cubic model where its edge (not rotated around the centre) is placed across the transmitter demonstrated a better performance in reducing the effect of [inline-formula removed] as compared to the sphere model while a cubic model where its corner (rotated around the centre) is placed across the transmitter demonstrated a worse performance than the spherical model. From this expression, it may be concluded that with the adjustment of topological system parameters the probability of successful reception ratio in MC may be possible.

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Year:  2020        PMID: 33010136      PMCID: PMC8676059          DOI: 10.1049/iet-nbt.2019.0300

Source DB:  PubMed          Journal:  IET Nanobiotechnol        ISSN: 1751-8741            Impact factor:   1.847


  4 in total

1.  Cubic membrane structure in amoeba (Chaos carolinensis) mitochondria determined by electron microscopic tomography.

Authors:  Y Deng; M Marko; K F Buttle; A Leith; M Mieczkowski; C A Mannella
Journal:  J Struct Biol       Date:  1999-10       Impact factor: 2.867

2.  APP processing and synaptic function.

Authors:  Flavio Kamenetz; Taisuke Tomita; Helen Hsieh; Guy Seabrook; David Borchelt; Takeshi Iwatsubo; Sangram Sisodia; Roberto Malinow
Journal:  Neuron       Date:  2003-03-27       Impact factor: 17.173

3.  Cubic membranes: a structure-based design for DNA uptake.

Authors:  Zakaria Almsherqi; Stephen Hyde; Malarmathy Ramachandran; Yuru Deng
Journal:  J R Soc Interface       Date:  2008-09-06       Impact factor: 4.118

Review 4.  Cubic membranes: a legend beyond the Flatland* of cell membrane organization.

Authors:  Zakaria A Almsherqi; Sepp D Kohlwein; Yuru Deng
Journal:  J Cell Biol       Date:  2006-06-19       Impact factor: 10.539

  4 in total

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