Literature DB >> 33009060

Dilation Modifies Association Between Symptoms and Esophageal Eosinophilia in Adult Patients With Eosinophilic Esophagitis.

Ekaterina Safroneeva1, Cary C Cotton2, Alain M Schoepfer3, Marcel Zwahlen1, John T Woosley4, Evan S Dellon2.   

Abstract

INTRODUCTION: We investigated whether dilation modifies the association between symptoms and esophageal eosinophilia (peak esophageal eosinophils/high-power field [eos/hpf]) in patients with eosinophilic esophagitis enrolled into a randomized trial comparing the efficacy of budesonide and fluticasone.
METHODS: Baseline Dysphagia Symptom Questionnaire and Eosinophilic Esophagitis Activity Index were available in 102 and 73 patients, respectively, of whom 56 and 39 underwent dilation at screening endoscopy before symptom assessment. The pair-wise relationship between Dysphagia Symptom Questionnaire, Eosinophilic Esophagitis Activity Index, and eos/hpf was analyzed with nonparametric correlations.
RESULTS: In nondilated patients, the association between baseline eos/hpf and symptoms was moderate and significant, although it was abolished in dilated patients. DISCUSSION: Dilation modifies association between symptoms and eos/hpf (clinicaltrials.gov NCT02019758).

Entities:  

Mesh:

Year:  2020        PMID: 33009060      PMCID: PMC7710608          DOI: 10.14309/ajg.0000000000000957

Source DB:  PubMed          Journal:  Am J Gastroenterol        ISSN: 0002-9270            Impact factor:   12.045


  13 in total

1.  Endoscopic assessment of the oesophageal features of eosinophilic oesophagitis: validation of a novel classification and grading system.

Authors:  Ikuo Hirano; Nelson Moy; Michael G Heckman; Colleen S Thomas; Nirmala Gonsalves; Sami R Achem
Journal:  Gut       Date:  2012-05-22       Impact factor: 23.059

Review 2.  A Conceptual Approach to Understanding Treatment Response in Eosinophilic Esophagitis.

Authors:  Evan S Dellon; Sandeep K Gupta
Journal:  Clin Gastroenterol Hepatol       Date:  2019-01-30       Impact factor: 11.382

Review 3.  Guidelines on eosinophilic esophagitis: evidence-based statements and recommendations for diagnosis and management in children and adults.

Authors:  Alfredo J Lucendo; Javier Molina-Infante; Ángel Arias; Ulrike von Arnim; Albert J Bredenoord; Christian Bussmann; Jorge Amil Dias; Mogens Bove; Jesús González-Cervera; Helen Larsson; Stephan Miehlke; Alexandra Papadopoulou; Joaquín Rodríguez-Sánchez; Alberto Ravelli; Jukka Ronkainen; Cecilio Santander; Alain M Schoepfer; Martin A Storr; Ingrid Terreehorst; Alex Straumann; Stephen E Attwood
Journal:  United European Gastroenterol J       Date:  2017-01-23       Impact factor: 4.623

4.  Outcomes of Esophageal Dilation in Eosinophilic Esophagitis: Safety, Efficacy, and Persistence of the Fibrostenotic Phenotype.

Authors:  Thomas M Runge; Swathi Eluri; Cary C Cotton; Caitlin M Burk; John T Woosley; Nicholas J Shaheen; Evan S Dellon
Journal:  Am J Gastroenterol       Date:  2016-01-12       Impact factor: 10.864

5.  Development and field testing of a novel patient-reported outcome measure of dysphagia in patients with eosinophilic esophagitis.

Authors:  E S Dellon; A-M Irani; M R Hill; I Hirano
Journal:  Aliment Pharmacol Ther       Date:  2013-07-09       Impact factor: 8.171

6.  Efficacy of Budesonide vs Fluticasone for Initial Treatment of Eosinophilic Esophagitis in a Randomized Controlled Trial.

Authors:  Evan S Dellon; John T Woosley; Ashley Arrington; Sarah J McGee; Jacquelyn Covington; Susan E Moist; Jessica H Gebhart; Alexandra E Tylicki; Shiyan O Shoyoye; Christopher F Martin; Joseph A Galanko; John A Baron; Nicholas J Shaheen
Journal:  Gastroenterology       Date:  2019-03-11       Impact factor: 22.682

7.  Inter- and intraobserver reliability and validation of a new method for determination of eosinophil counts in patients with esophageal eosinophilia.

Authors:  Evan S Dellon; Karen J Fritchie; Tara C Rubinas; John T Woosley; Nicholas J Shaheen
Journal:  Dig Dis Sci       Date:  2009-10-15       Impact factor: 3.199

8.  Development and validation of a symptom-based activity index for adults with eosinophilic esophagitis.

Authors:  Alain M Schoepfer; Alex Straumann; Radoslaw Panczak; Michael Coslovsky; Claudia E Kuehni; Elisabeth Maurer; Nadine A Haas; Yvonne Romero; Ikuo Hirano; Jeffrey A Alexander; Nirmala Gonsalves; Glenn T Furuta; Evan S Dellon; John Leung; Margaret H Collins; Christian Bussmann; Peter Netzer; Sandeep K Gupta; Seema S Aceves; Mirna Chehade; Fouad J Moawad; Felicity T Enders; Kathleen J Yost; Tiffany H Taft; Emily Kern; Marcel Zwahlen; Ekaterina Safroneeva
Journal:  Gastroenterology       Date:  2014-08-23       Impact factor: 22.682

9.  ACG clinical guideline: Evidenced based approach to the diagnosis and management of esophageal eosinophilia and eosinophilic esophagitis (EoE).

Authors:  Evan S Dellon; Nirmala Gonsalves; Ikuo Hirano; Glenn T Furuta; Chris A Liacouras; David A Katzka
Journal:  Am J Gastroenterol       Date:  2013-04-09       Impact factor: 10.864

Review 10.  Esophageal dilation with either bougie or balloon technique as a treatment for eosinophilic esophagitis: a systematic review and meta-analysis.

Authors:  Michael Dougherty; Thomas M Runge; Swathi Eluri; Evan S Dellon
Journal:  Gastrointest Endosc       Date:  2017-04-28       Impact factor: 10.396

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  5 in total

1.  A Clinical Severity Index for Eosinophilic Esophagitis: Development, Consensus, and Future Directions.

Authors:  Evan S Dellon; Paneez Khoury; Amanda B Muir; Chris A Liacouras; Ekaterina Safroneeva; Dan Atkins; Margaret H Collins; Nirmala Gonsalves; Gary W Falk; Jonathan M Spergel; Ikuo Hirano; Mirna Chehade; Alain M Schoepfer; Calies Menard-Katcher; David A Katzka; Peter A Bonis; Albert J Bredenoord; Bob Geng; Elizabeth T Jensen; Robert D Pesek; Paul Feuerstadt; Sandeep K Gupta; Alfredo J Lucendo; Robert M Genta; Girish Hiremath; Emily C McGowan; Fouad J Moawad; Kathryn A Peterson; Marc E Rothenberg; Alex Straumann; Glenn T Furuta; Seema S Aceves
Journal:  J Allergy Clin Immunol       Date:  2022-05-20       Impact factor: 14.290

2.  A Clinical Severity Index for Eosinophilic Esophagitis: Development, Consensus, and Future Directions.

Authors:  Evan S Dellon; Paneez Khoury; Amanda B Muir; Chris A Liacouras; Ekaterina Safroneeva; Dan Atkins; Margaret H Collins; Nirmala Gonsalves; Gary W Falk; Jonathan M Spergel; Ikuo Hirano; Mirna Chehade; Alain M Schoepfer; Calies Menard-Katcher; David A Katzka; Peter A Bonis; Albert J Bredenoord; Bob Geng; Elizabeth T Jensen; Robert D Pesek; Paul Feuerstadt; Sandeep K Gupta; Alfredo J Lucendo; Robert M Genta; Girish Hiremath; Emily C McGowan; Fouad J Moawad; Kathryn A Peterson; Marc E Rothenberg; Alex Straumann; Glenn T Furuta; Seema S Aceves
Journal:  Gastroenterology       Date:  2022-05-20       Impact factor: 33.883

3.  Development of a core outcome set for therapeutic studies in eosinophilic esophagitis (COREOS).

Authors:  Christopher Ma; Alain M Schoepfer; Evan S Dellon; Albert J Bredenoord; Mirna Chehade; Margaret H Collins; Brian G Feagan; Glenn T Furuta; Sandeep K Gupta; Ikuo Hirano; Vipul Jairath; David A Katzka; Rish K Pai; Marc E Rothenberg; Alex Straumann; Seema S Aceves; Jeffrey A Alexander; Nicoleta C Arva; Dan Atkins; Luc Biedermann; Carine Blanchard; Antonella Cianferoni; Constanza Ciriza de Los Rios; Frederic Clayton; Carla M Davis; Nicola de Bortoli; Jorge A Dias; Gary W Falk; Robert M Genta; Gisoo Ghaffari; Nirmala Gonsalves; Thomas Greuter; Russell Hopp; Karen S Hsu Blatman; Elizabeth T Jensen; Doug Johnston; Amir F Kagalwalla; Helen M Larsson; John Leung; Hubert Louis; Joanne C Masterson; Calies Menard-Katcher; Paul A Menard-Katcher; Fouad J Moawad; Amanda B Muir; Vincent A Mukkada; Roberto Penagini; Robert D Pesek; Kathryn Peterson; Philip E Putnam; Alberto Ravelli; Edoardo V Savarino; Christoph Schlag; Philipp Schreiner; Dagmar Simon; Thomas C Smyrk; Jonathan M Spergel; Tiffany H Taft; Ingrid Terreehorst; Tim Vanuytsel; Carina Venter; Mario C Vieira; Michael Vieth; Berber Vlieg-Boerstra; Ulrike von Arnim; Marjorie M Walker; Joshua B Wechsler; Philip Woodland; John T Woosley; Guang-Yu Yang; Noam Zevit; Ekaterina Safroneeva
Journal:  J Allergy Clin Immunol       Date:  2021-07-06       Impact factor: 10.793

4.  Long-Lasting Dissociation of Esophageal Eosinophilia and Symptoms After Dilation in Adults With Eosinophilic Esophagitis.

Authors:  Ekaterina Safroneeva; Zhaoxing Pan; Eileen King; Lisa J Martin; Margaret H Collins; Guang-Yu Yang; Kelley E Capocelli; Nicoleta C Arva; J Pablo Abonia; Dan Atkins; Peter A Bonis; Evan S Dellon; Gary W Falk; Nirmala Gonsalves; Sandeep K Gupta; Ikuo Hirano; John Leung; Paul A Menard-Katcher; Vincent A Mukkada; Alain M Schoepfer; Jonathan M Spergel; Barry K Wershil; Marc E Rothenberg; Seema S Aceves; Glenn T Furuta
Journal:  Clin Gastroenterol Hepatol       Date:  2021-05-29       Impact factor: 11.382

5.  Mental distress among adult patients with eosinophilic esophagitis.

Authors:  Willemijn E de Rooij; Floor Bennebroek Evertsz'; A Lei; Albert J Bredenoord
Journal:  Neurogastroenterol Motil       Date:  2020-12-31       Impact factor: 3.598

  5 in total

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