Literature DB >> 33002574

De novo assembly and functional annotation of the Red-striped golden stink bug (Poecilocoris lewisi) transcriptome.

Seokhyun Lee1, Joon Ha Lee2, Ra Ham Lee3, Yong Pyo Shin4, In-Woo Kim5, Minchul Seo6, Mi-Ae Kim7, Jae Sam Hwang8, Donghyun Shin9, Hak-Kyo Lee10.   

Abstract

Insect antimicrobial peptides (AMPs) have a wide range of functions and potential applications, and have recently attracted attention as alternative foods and medicines for humans. Our study performed transcriptome analysis to explore the potential of the red-striped golden stink bug (Poecilocoris lewisi), and as a result, we have discovered new features of P. lewisi that have not been identified. Specifically, defensin found in P. lewisi is a well-known AMP and is expressed by various plants, animals and fungi for host defense. Moreover, the discovery of defensin in P. lewisi provides new research and important information. In this study, we identified AMP and related DEG in P. lewisi that are closely related to human disease and immune response. These findings will provide the basis and important information for future research on P. lewisi that has not yet been studied.
Copyright © 2020. Published by Elsevier B.V.

Entities:  

Keywords:  Antimicrobial peptide; Disease; Insect; Poecilocoris lewisi; Transcriptomics

Mesh:

Year:  2020        PMID: 33002574     DOI: 10.1016/j.gene.2020.145188

Source DB:  PubMed          Journal:  Gene        ISSN: 0378-1119            Impact factor:   3.688


  1 in total

1.  Antitumorigenic effect of insect-derived peptide poecilocorisin-1 in human skin cancer cells through regulation of Sp1 transcription factor.

Authors:  Ra Ham Lee; Jae-Don Oh; Jae Sam Hwang; Hak-Kyo Lee; Donghyun Shin
Journal:  Sci Rep       Date:  2021-09-16       Impact factor: 4.379

  1 in total

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