Literature DB >> 3300155

Production of authentic recombinant somatropin.

L Fryklund.   

Abstract

Further developments in recombinant DNA technology, exploiting a natural mechanism for export using a signal peptide in E. coli, have enabled the production of recombinant somatropin, with full biological activity and extremely high purity. The secretion of the protein into the periplasmic space has simplified purification procedures, providing a unique and simple process and a pure and active product.

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Year:  1987        PMID: 3300155     DOI: 10.1111/j.1651-2227.1987.tb17090.x

Source DB:  PubMed          Journal:  Acta Paediatr Scand Suppl        ISSN: 0300-8843


  3 in total

Review 1.  Optimum use of growth hormone in children.

Authors:  Z Laron; O Butenandt
Journal:  Drugs       Date:  1991-07       Impact factor: 9.546

2.  Human growth hormone stimulates liver regeneration in rats.

Authors:  K Asakawa; N Hizuka; K Takano; R Horikawa; I Sukegawa; C Toyoda; K Shizume
Journal:  J Endocrinol Invest       Date:  1989-05       Impact factor: 4.256

Review 3.  Biosynthetic growth hormone therapy in children with growth hormone deficiency: experience at AIIMS, New Delhi.

Authors:  P S Menon; A Virmani; A K Sethi
Journal:  Indian J Pediatr       Date:  1991 Sep-Oct       Impact factor: 1.967

  3 in total

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