| Literature DB >> 33001013 |
Banoth Karan Kumar1, Kondapalli Venkata Gowri Chandra Sekhar2, Selvaraj Kunjiappan3, Joazaizulfazli Jamalis4, Rafael Balaña-Fouce5, Murugesan Sankaranarayanan1.
Abstract
β-Carboline, a naturally occurring indole alkaloid, holds a momentous spot in the field of medicinal chemistry due to its myriad of pharmacological actions like anticancer, antiviral, antibacterial, antifungal, antileishmanial, antimalarial, neuropharmacological, anti-inflammatory and antithrombotic among others. β-Carbolines exhibit their pharmacological activity via diverse mechanisms. This review provides a recent update (2015-2020) on the anti-infective potential of natural and synthetic β-carboline analogs focusing on its antibacterial, antifungal, antiviral, antimalarial, antileishmanial and antitrypanosomal properties. In cases where enough details are available, a note on its mechanism of action is also added. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.Entities:
Keywords: PYRIDO indole; antibacterial; antifungal; antiprotozoal; antiviral; β-Carboline
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Year: 2021 PMID: 33001013 DOI: 10.2174/1389557520666201001130114
Source DB: PubMed Journal: Mini Rev Med Chem ISSN: 1389-5575 Impact factor: 3.862