Literature DB >> 33001013

Recent Update on the Anti-infective Potential of β-carboline Analogs.

Banoth Karan Kumar1, Kondapalli Venkata Gowri Chandra Sekhar2, Selvaraj Kunjiappan3, Joazaizulfazli Jamalis4, Rafael Balaña-Fouce5, Murugesan Sankaranarayanan1.   

Abstract

β-Carboline, a naturally occurring indole alkaloid, holds a momentous spot in the field of medicinal chemistry due to its myriad of pharmacological actions like anticancer, antiviral, antibacterial, antifungal, antileishmanial, antimalarial, neuropharmacological, anti-inflammatory and antithrombotic among others. β-Carbolines exhibit their pharmacological activity via diverse mechanisms. This review provides a recent update (2015-2020) on the anti-infective potential of natural and synthetic β-carboline analogs focusing on its antibacterial, antifungal, antiviral, antimalarial, antileishmanial and antitrypanosomal properties. In cases where enough details are available, a note on its mechanism of action is also added. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Entities:  

Keywords:  PYRIDO indole; antibacterial; antifungal; antiprotozoal; antiviral; β-Carboline

Mesh:

Substances:

Year:  2021        PMID: 33001013     DOI: 10.2174/1389557520666201001130114

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN: 1389-5575            Impact factor:   3.862


  2 in total

1.  Antimicrobial Activity of a Repurposed Harmine-Derived Compound on Carbapenem-Resistant Acinetobacter baumannii Clinical Isolates.

Authors:  Anke Breine; Mégane Van Gysel; Mathias Elsocht; Clémence Whiteway; Chantal Philippe; Théo Quinet; Adam Valcek; Johan Wouters; Steven Ballet; Charles Van der Henst
Journal:  Front Cell Infect Microbiol       Date:  2022-01-24       Impact factor: 5.293

Review 2.  Indole-Based Tubulin Inhibitors: Binding Modes and SARs Investigations.

Authors:  Sheng Tang; Zhihui Zhou; Zhiyan Jiang; Wufu Zhu; Dan Qiao
Journal:  Molecules       Date:  2022-02-28       Impact factor: 4.411

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.