Shoubin Li1, Yi Jia2, Chunhong Yu3, Helong Xiao4, Liuxiong Guo5, Fuzhen Sun6, Dong Wei7, Panying Zhang8, Jingpo Li9, Junjiang Liu10. 1. Department of Urology, Hebei General Hospital, , Shijiazhuang, Hebei, China. lishoubin@163.com. 2. Department of Urology, Hebei General Hospital, , Shijiazhuang, Hebei, China. jia930529@vip.qq.com. 3. Department of Medical Checkup Centre, Hebei General Hospital,, Shijiazhuang, Hebei, China. sdyuchunhong@163.com. 4. Department of Urology, Hebei General Hospital, , Shijiazhuang, Hebei, China. egone1989@sina.com. 5. Department of Urology, Hebei General Hospital, , Shijiazhuang, Hebei, China. 175629871@qq.com. 6. Department of Urology, Hebei General Hospital, , Shijiazhuang, Hebei, China. sfz20050122@sina.com. 7. Department of Urology, Hebei General Hospital, , Shijiazhuang, Hebei, China. weidong051222@163.com. 8. Department of Urology, Hebei General Hospital, , Shijiazhuang, Hebei, China. zhangpy666@126.com. 9. Department of Urology, Hebei General Hospital, , Shijiazhuang, Hebei, China. 1265038353@qq.com. 10. Department of Urology, Hebei General Hospital, , Shijiazhuang, Hebei, China. liujunjiang67@163.com.
Abstract
PURPOSE: To compare the influence of three operative approaches [transurethral en bloc resection of bladder tumor by pin-shaped electrode (pin-ERBT), transurethral resection of bladder tumor (TURBT) and transurethral holmium laser resection of bladder tumor (HoLRBT)] on the recurrence rate of non-muscle-invasive bladder cancer (NMIBC) at low dimension (i.e. diameter below 3 cm). MATERIALS AND METHODS: A retrospective analysis was conducted for a total of 115 patients affected by solitary NMIBC, with a diameter <3 cm, who were submitted to operation between March 2013 to May 2017. The patients were divided according to the operative method applied (pin-ERBT, TURBT and HoLRBT groups, respectively). The 2-year recurrence rate was compared among the three groups, and multivariat Cox hazard model analysis was applied to analyze the influencing factor(s) for postoperative recurrence. RESULTS: The 2-year recurrence rate was 10.0% in ERBT, 38.5% in TURBT and 40.0% in HoLRBT group, with a significant difference (P =0.014). According to the Cox hazard model analysis, age(HR=1.058, 95% CI: 1.019~1.098，P=0.003), operative method(HR=2.974,6.508, 95% CI: 0.862~10.255,1.657~25.566, P=0.023), smoking(HR=2.399, 95% CI: 1.147~5.017, P=0.020) and pathological grade(HR=2.012,95% CI: 1.279~3.165, P=0.002) were risk factors for postoperative recurrence of bladder cancer. CONCLUSION: Pin-ERBT can prominently decrease the postoperative recurrence rate of solitary NMIBC with a diameter <3 cm.
PURPOSE: To compare the influence of three operative approaches [transurethral en bloc resection of bladder tumor by pin-shaped electrode (pin-ERBT), transurethral resection of bladder tumor (TURBT) and transurethral holmium laser resection of bladder tumor (HoLRBT)] on the recurrence rate of non-muscle-invasive bladder cancer (NMIBC) at low dimension (i.e. diameter below 3 cm). MATERIALS AND METHODS: A retrospective analysis was conducted for a total of 115 patients affected by solitary NMIBC, with a diameter <3 cm, who were submitted to operation between March 2013 to May 2017. The patients were divided according to the operative method applied (pin-ERBT, TURBT and HoLRBT groups, respectively). The 2-year recurrence rate was compared among the three groups, and multivariat Cox hazard model analysis was applied to analyze the influencing factor(s) for postoperative recurrence. RESULTS: The 2-year recurrence rate was 10.0% in ERBT, 38.5% in TURBT and 40.0% in HoLRBT group, with a significant difference (P =0.014). According to the Cox hazard model analysis, age(HR=1.058, 95% CI: 1.019~1.098，P=0.003), operative method(HR=2.974,6.508, 95% CI: 0.862~10.255,1.657~25.566, P=0.023), smoking(HR=2.399, 95% CI: 1.147~5.017, P=0.020) and pathological grade(HR=2.012,95% CI: 1.279~3.165, P=0.002) were risk factors for postoperative recurrence of bladder cancer. CONCLUSION: Pin-ERBT can prominently decrease the postoperative recurrence rate of solitary NMIBC with a diameter <3 cm.
Authors: D Oswald; P Pallauf; S Deininger; T R W Herrmann; C Netsch; B Becker; M Fiedler; A Haecker; R Homberg; J T Klein; K Lehrich; A Miernik; P Olbert; D S Schöb; K D Sievert; A J Gross; J Westphal; L Lusuardi Journal: Urologie Date: 2022-03-14