| Literature DB >> 33000076 |
Tsutomu Iwasaki1, Toru Hifumi1, Kuniyoshi Hayashi2, Norio Otani1, Shinichi Ishimatsu1.
Abstract
OBJECTIVE: Even if performing rapid influenza diagnostic tests test will not change clinical decision making, we sometimes perform at triage to reduce length of stay in Japan. Whether performing rapid influenza diagnostic tests at triage may shorten emergency department (ED) length of stay (LOS) is remains unclear. We aimed to determine the utility of rapid influenza diagnostic tests at triage in shortening ED length of stay LOS.Entities:
Keywords: crowding; emergency department; influenza; length of stay; point‐of‐care testing; propensity score; triage
Year: 2020 PMID: 33000076 PMCID: PMC7493520 DOI: 10.1002/emp2.12125
Source DB: PubMed Journal: J Am Coll Emerg Physicians Open ISSN: 2688-1152
FIGURE 1Patient flow through the emergency department. RIDT, rapid influenza diagnostic test
FIGURE 2Patient selection process. ED, emergency department; RIDT, rapid influenza diagnostic test
Baseline characteristics
| Before PS matching | After PS matching | |||||
|---|---|---|---|---|---|---|
| Triage group (n = 363) | After examination group (n = 2191) | Standardized difference (%) | Triage group (n = 329) | After examination group (n = 329) | Standardized difference (%) | |
| Age (y), mean (SD) | 40.5 ± 15.0 | 43.3 ± 17.5 | 0.175 | 40.8 ± 15.1 | 41.3 ± 16.7 | 0.033 |
| Sex (male) | 200 (55.1%) | 1,016 (46.4%) | 0.175 | 173 (52.6%) | 172 (52.3%) | 0.006 |
| Risk factors for influenza‐related complications | 98 (27.0%) | 819 (37.4%) | 0.224 | 96 (29.2%) | 95 (28.9%) | 0.007 |
| Any of the following symptoms: | 363 (100%) | 2,169 (99.0%) | 0.142 | 329 (100%) | 329 (100%) | NA |
| Fever | 350 (96.4%) | 2,009 (91.7%) | 0.201 | 316 ( (96.0%) | 319 (97.0%) | 0.050 |
| Chill | 129 (35.5%) | 846 (38.6%) | 0.064 | 119 (36.2%) | 119 (36.2%) | 0 |
| Fatigue | 77 (21.2%) | 397 (18.1%) | 0.078 | 68 (20.7%) | 67 (20.4%) | 0.008 |
| Cough | 236 (65.0%) | 1,528 (69.7%) | 0.101 | 214 (65.0%) | 225 (68.4%) | 0.071 |
| Nasal discharge | 163 (44.9%) | 1,119 (51.1%) | 0.124 | 152 (46.2%) | 157 (47.7%) | 0.030 |
| Throat pain | 220 (60.6%) | 1,354 (61.8%) | 0.024 | 202 (61.4%) | 208 (63.2%) | 0.038 |
| Joint pain | 160 (44.1%) | 1,094 (49.9%) | 0.118 | 143 (43.5%) | 135 (41.0%) | 0.049 |
| Headache | 133 (36.6%) | 1,000 (45.6%) | 0.184 | 127 (38.6%) | 127 (38.6%) | 0 |
| Sputum production | 84 (23.1%) | 697 (31.8%) | 0.195 | 80 (24.3%) | 85 (25.8%) | 0.035 |
| Muscle pain | 48 (13.2%) | 282 (12.9%) | 0.010 | 44 (13.4%) | 34 (10.3%) | 0.094 |
| Vital signs | ||||||
| Temperature (°C), mean (SD) | 38.2 ± 0.8 | 38.1 ± 0.9 | 0.115 | 38.2 ± 0.8 | 38.1 ± 0.9 | 0.076 |
| Pulse rate (bpm), mean (SD) | 101.3 ± 15.3 | 100.1 ± 16.5 | 0.073 | 101.2 ± 15.5 | 100.2 ± 15.5 | 0.068 |
| MAP (mm Hg), mean (SD) | 91.3 ± 14.2 | 92.3 ± 15.1 | 0.068 | 90.9 ± 14.4 | 91.4 ± 14.7 | 0.032 |
| JTAS score | 0.255 | 0.040 | ||||
| 1 | 0 | 0 | 0 | 0 | ||
| 2 | 5 (1.4%) | 72 (3.3%) | 5 (1.5%) | 4 (1.2%) | ||
| 3 | 94 ( (25.9%) | 773 (35.3%) | 88 (26.7%) | 84 (25.5%) | ||
| 4 | 261 (71.9%) | 1,327 (60.6%) | 234 (71.1%) | 239 (72.6%) | ||
| 5 | 3 (0.8%) | 19 (0.9%) | 2 (0.6%) | 2 (0.6%) | ||
| Positive RIDT (A or B) | 187 (51.5%) | 756 (34.5%) | 0.349 | 162 (49.2%) | 160 (48.6%) | 0.012 |
| Arrival‐to‐triage time (min), median (IQR) | 19 (12–32) | 14 (9–22) | 0.394 | 18 (12–28) | 17 (10–29) | 0.003 |
MAP, systolic pressure + 2 × diastolic pressure)/3. Arrival‐to‐triage time, from the time the patient was registered to the ED index to the triage time recorded on the triage template. Risk factors for influenza‐related complications are described in detail in the Supporting Information Appendix S2.
ED, emergency department; IQR, interquartile range; JTAS, Japan Triage and Acuity Scale; MAP, mean arterial pressure; PS, propensity score; RIDT, rapid influenza diagnostic test.
Emergency department length of stay
| Before PS matching | After PS matching | |||||
|---|---|---|---|---|---|---|
| Triage group (n = 363) | After examination group (n = 2191) | Median difference (95% CI) | Triage (n = 329) | After examination group (n = 329) | Median difference (95% CI) | |
| ED length of stay (min), median (IQR) | 83 (61–114) | 100 (76–137) | 16 (12–21) | 81 (60–111) | 106 (80–142) | 24 (17–30) |
| Arrival‐to‐order time (min), median (IQR) | 25 (15–35) | 45 (31–64) | 20 (18–22) | 23 (14–34) | 52 (33–74) | 26 (22–30) |
| Order‐to‐result time (min), median (IQR) | 18 (15–24) | 18 (15–24) | 0 (−1–0) | 18 (15–23) | 18 (14–23) | 0 (−1–0) |
| Result‐to‐discharge time (min), median (IQR) | 32 (20–56) | 26 (17–47) | −5 (−7 to −2) | 32 (20–56) | 28 (17–46) | −4 (−7 to −1) |
Arrival‐to‐order time, from the time patients was registered to ED index to the time RIDT was ordered at medical chart. Order‐to‐result time, from the time RIDT was ordered on the medical chart to the time the RIDT result was recorded on the medical chart. Result‐to‐discharge time, from the time the RIDT result was recorded on the medical chart to the time patient had completed payment.
CI, confidence interval; IQR, interquartile range; PS, propensity score; RIDT, rapid influenza diagnostic test.
FIGURE 3Kaplan‐Meier curves for time spent in the emergency department.*P < 0.05 was considered statistically significant. ED, emergency department
Secondary outcomes
| Before PS matching | After PS matching | |||||
|---|---|---|---|---|---|---|
| Triage group (n = 363) | After examination group (n = 2191) | Odds ratio (95% CI) | Triage group (n = 329) | After examination group (n = 329) | Odds ratio (95% CI) | |
| Further test | 25 (6.9%) | 529 (24.1%) | 0.23 (0.15–0.35) | 25 (7.6%) | 73 (22.2%) | 0.29 (0.17–0.48) |
| Chest radiograph | 16 (4.4%) | 317 (14.5%) | 0.27 (0.15–0.46) | 16 (4.9%) | 40 (12.2%) | 0.37 (0.19–0.69) |
| Computed tomography of chest | 0 | 23 (1.0%) | 0 (0–1.04) | 0 | 3 (0.9%) | 0 (0–2.42) |
| Blood test | 16 (4.4%) | 336 (15.3%) | 0.25 (0.14–0.43) | 16 (4.9%) | 44 (13.4%) | 0.33 (0.17–0.62) |
| Blood culture | 12 (3.3%) | 155 (7.1%) | 0.45 (0.22–0.82) | 12 (3.6%) | 14 (4.3%) | 0.85 (0.35–2.02) |
| Urine test | 7 (1.9%) | 151 (6.9%) | 0.27 (0.10–0.57) | 7 (2.1%) | 14 (4.3%) | 0.49 (0.16–1.31) |
| Urine culture | 0 | 7 (0.3%) | 0 (0–4.19) | 0 | 0 | NA |
| Cerebrospinal fluid analysis | 0 | 0 | NA | 0 | 0 | NA |
| Any parenteral medications | 17 (4.7%) | 272 (12.4%) | 0.34 (0.20–0.57) | 16 (4.9%) | 38 (11.6%) | 0.39 (0.20–0.74) |
| Parenteral antibiotics | 2 (0.6%) | 50 (2.3%) | 0.23 (0.03–0.91) | 2 (0.6%) | 2 (0.6%) | 1 (0.07–13.90) |
| Any prescription | 136 (37.5%) | 951 (43.4%) | 0.78 (0.62–0.99) | 129 (39.2%) | 137 (41.6%) | 0.90 (0.65–1.25) |
| Antibiotic prescription | 17 (4.7%) | 203 (9.3%) | 0.48 (0.27–0.80) | 16 (4.9%) | 25 (7.6%) | 0.62 (0.30–1.24) |
| Any anti‐influenza medications | 44 (12.1%) | 216 (9.9%) | 1.26 (0.87–1.79) | 42 (12.8%) | 38 (11.6%) | 1.12 (0.68–1.84) |
| Bounce‐back admission within 3 days | 0 | 28 (1.3%) | 0 (0–0.84) | 0 | 2 (0.6%) | 0 (0–5.32) |
| Bounce‐back admission within 7 days | 0 (16.3%) | 42 (1.9%) | 0 (0–0.55) | 0 | 3 (0.9%) | 0 (0–2.42) |
|
Median Difference (95% CI) |
Median Difference (95% CI) | |||||
| Cost (yen, thousand), median (IQR) | 14.3 (12.1–17.2) | 14.6 (11.5–18.7) | 6.4 (0.50–12.70) | 14.3 (11.9–17.2) | 15.0 (12.4–18.5) | 10.7 (2.60–18.50) |
CI, confidence interval; IQR, interquartile range; NA, not applicable; PS, propensity score.