Elena Cavarretta1,2, Annachiara Pingitore3, Stefania Della Porta4, Riccardo Capitani4, Marco Bernardi4, Luigi Sciarra5, Andrea Saglietto6, Francesco Versaci7, Camillo Autore3, Fabrizio Perroni8, Giuseppe Biondi-Zoccai9,10, Giacomo Frati9,11, Mariangela Peruzzi10. 1. Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University, Latina, Italy - elena.cavarretta@uniroma1.it. 2. Mediterranea Cardiocentro, Naples, Italy - elena.cavarretta@uniroma1.it. 3. Department of Clinical and Molecular Medicine, Sapienza University, Rome, Italy. 4. Department of Physiology and Pharmacology, Sapienza University, Rome, Italy. 5. Division of Cardiology, Casilino Polyclinic, Rome, Italy. 6. Division of Cardiology, Department of Medical Sciences, Città della Salute e della Scienza, University of Turin, Turin, Italy. 7. Division of Cardiology, S. Maria Goretti Hospital, Latina, Italy. 8. Section of Exercise and Health Sciences, Department of Biomolecular Sciences, University of Urbino Carlo Bo, Urbino, Italy. 9. Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University, Latina, Italy. 10. Mediterranea Cardiocentro, Naples, Italy. 11. Department of Angio-Cardio-Neurology, IRCCS NeuroMed, Pozzilli, Isernia, Italy.
Abstract
INTRODUCTION: The impact of the International Criteria for ECG interpretation in athletes has further improved the diagnostic accuracy of the 12-lead ECG use for preparticipation screening (PPS); moreover, these criteria have been evaluated in different populations of athletes and settings proving good results. EVIDENCE ACQUISITION: We aimed to perform a comprehensive review of the use of the International Criteria for ECG interpretation in athletes, stemming from a systematic review to diagnostic meta-analysis, limiting our inclusion only to observational studies to determine the diagnostic accuracy of ECG for detecting cardiac anomalies related to sudden cardiac death in athletes. EVIDENCE SYNTHESIS: This meta-analysis is expected to include several important studies related to PPS on different populations of athletes comparing different ECG criteria and detail important data on the diagnostic accuracy of ECG in PPS. Furthermore, we intend to highlight the advantage of using ECG in PPS. CONCLUSIONS: The present diagnostic meta-analysis results will aid sports medicine physicians and cardiologist in adhering to the most accurate criteria for ECG evaluation in athletes and it may help to solve controversies aroused regarding the excess cost of ECG in PPS related to the amount of false positive cases.
INTRODUCTION: The impact of the International Criteria for ECG interpretation in athletes has further improved the diagnostic accuracy of the 12-lead ECG use for preparticipation screening (PPS); moreover, these criteria have been evaluated in different populations of athletes and settings proving good results. EVIDENCE ACQUISITION: We aimed to perform a comprehensive review of the use of the International Criteria for ECG interpretation in athletes, stemming from a systematic review to diagnostic meta-analysis, limiting our inclusion only to observational studies to determine the diagnostic accuracy of ECG for detecting cardiac anomalies related to sudden cardiac death in athletes. EVIDENCE SYNTHESIS: This meta-analysis is expected to include several important studies related to PPS on different populations of athletes comparing different ECG criteria and detail important data on the diagnostic accuracy of ECG in PPS. Furthermore, we intend to highlight the advantage of using ECG in PPS. CONCLUSIONS: The present diagnostic meta-analysis results will aid sports medicine physicians and cardiologist in adhering to the most accurate criteria for ECG evaluation in athletes and it may help to solve controversies aroused regarding the excess cost of ECG in PPS related to the amount of false positive cases.
Authors: Elena Cavarretta; Luigi Sciarra; Giuseppe Biondi-Zoccai; Francesco Maffessanti; Antonia Nigro; Fabio Sperandii; Emanuele Guerra; Federico Quaranta; Chiara Fossati; Mariangela Peruzzi; Annachiara Pingitore; Dimitrios M Stasinopoulos; Robert A Rigby; Rachele Adorisio; Andrea Saglietto; Leonardo Calò; Giacomo Frati; Fabio Pigozzi Journal: Front Cardiovasc Med Date: 2022-02-03