Literature DB >> 32994267

Leclercia adecarboxylata causing necrotising soft tissue infection in an immunocompetent adult.

Molly K Lonneman1, Rebekah J Devasahayam2, Cody J Phillips3.   

Abstract

A 72-year-old woman presented with concern for a necrotising soft tissue infection (NSTI) 6 days after a tree branch impaled her left lower extremity while hiking in Hawaii. The wound was irrigated and closed at a local clinic in Hawaii. She completed a 5-day course of clindamycin. She presented to our emergency department 1 day after completion of antibiotics due to worsening erythema and malodorous drainage. Local wound exploration revealed bullae and easy dissection of fascial planes. CT scan revealed complex heterogeneous fluid and inflammatory stranding in the posterior calf. Clinical and radiographic findings raised concern for NSTI prompting initiation of broad spectrum antibiotics and urgent operative debridement. Wound cultures and deep tissues cultures returned positive for pansusceptible Leclercia adecarboxylata She underwent two additional operative debridements and transitioned to negative pressure wound therapy during her hospitalisation. She was discharged home on oral amoxicillin/clavulanate on hospital day 6. © BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  accidents; general surgery; infections; injuries; plastic and reconstructive surgery; tropical medicine (infectious disease)

Mesh:

Substances:

Year:  2020        PMID: 32994267      PMCID: PMC7526306          DOI: 10.1136/bcr-2020-235633

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  19 in total

Review 1.  Matrix-assisted laser desorption ionization-time of flight mass spectrometry: a fundamental shift in the routine practice of clinical microbiology.

Authors:  Andrew E Clark; Erin J Kaleta; Amit Arora; Donna M Wolk
Journal:  Clin Microbiol Rev       Date:  2013-07       Impact factor: 26.132

2.  Wound closure of leg fasciotomy: comparison of vacuum-assisted closure versus shoelace technique. A randomised study.

Authors:  D Kakagia; E J Karadimas; G Drosos; A Ververidis; G Trypsiannis; D Verettas
Journal:  Injury       Date:  2012-02-28       Impact factor: 2.586

Review 3.  Skin, soft tissue and systemic bacterial infections following aquatic injuries and exposures.

Authors:  James H Diaz; Fred A Lopez
Journal:  Am J Med Sci       Date:  2015-03       Impact factor: 2.378

Review 4.  Leclercia adecarboxylata infections: case report and review.

Authors:  Z Temesgen; D R Toal; F R Cockerill
Journal:  Clin Infect Dis       Date:  1997-07       Impact factor: 9.079

5.  Is Leclercia adecarboxylata a new and unfamiliar marine pathogen?

Authors:  Yaniv Keren; Doron Keshet; Mark Eidelman; Yuval Geffen; Ayelet Raz-Pasteur; Khetam Hussein
Journal:  J Clin Microbiol       Date:  2014-02-12       Impact factor: 5.948

Review 6.  Antimicrobial prophylaxis for wounds and procedures in the emergency department.

Authors:  Gregory J Moran; David A Talan; Fredrick M Abrahamian
Journal:  Infect Dis Clin North Am       Date:  2008-03       Impact factor: 5.982

7.  Isolation and characterization of multidrug-resistant Leclercia species from animal clinical case.

Authors:  M Choudhary; B K Choudhary; S Bhoyar; S B Kale; S P Chaudhari; B C Bera; A Jain; S B Barbuddhe
Journal:  Lett Appl Microbiol       Date:  2017-12-07       Impact factor: 2.858

8.  Antibiotics to prevent infection of simple wounds: a meta-analysis of randomized studies.

Authors:  P Cummings; M A Del Beccaro
Journal:  Am J Emerg Med       Date:  1995-07       Impact factor: 2.469

9.  Natural antimicrobial susceptibility patterns and biochemical profiles of Leclercia adecarboxylata strains.

Authors:  I Stock; S Burak; B Wiedemann
Journal:  Clin Microbiol Infect       Date:  2004-08       Impact factor: 8.067

10.  Draft Genome Sequence of NDM-1-Producing Leclercia adecarboxylata.

Authors:  Yannick Hoyos-Mallecot; María Dolores Rojo-Martín; Rémy A Bonnin; Elodie Creton; Jose María Navarro Marí; Thierry Naas
Journal:  Genome Announc       Date:  2017-04-27
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