Literature DB >> 329910

A phase II clinical trial of prednimustine. Clinical screening cooperative group of E.O.R.T.C.

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Abstract

In a phase II trial, prednimustine was often efficient in treating chronic lymphoid leukaemia (CLL) patients and was also active in some patients with lymphosarcoma, melanoma and bronchus carcinoma. Tolerance was generally excellent, the most critical side effect being thrombocytopenia in the case of CLL.

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Year:  1977        PMID: 329910

Source DB:  PubMed          Journal:  Biomedicine        ISSN: 0300-0893


  8 in total

Review 1.  Chemotherapy of malignant melanoma.

Authors:  R S Benjamin
Journal:  World J Surg       Date:  1979-07-30       Impact factor: 3.352

Review 2.  New cancer chemotherapy drugs in Europe.

Authors:  G Mathé; L M van Putten
Journal:  Cancer Chemother Pharmacol       Date:  1978       Impact factor: 3.333

Review 3.  Developing new drugs for ovarian cancer: a challenging task in a changing reality.

Authors:  R M Canetta; S K Carter
Journal:  J Cancer Res Clin Oncol       Date:  1984       Impact factor: 4.553

4.  Prednimustine in combination with methotrexate and 5-fluorouracil in advanced breast cancer: a phase I-II study.

Authors:  H T Mouridsen; E Boesen
Journal:  Breast Cancer Res Treat       Date:  1983       Impact factor: 4.872

5.  Phase II trial of prednimustine (NSC-134087) in the treatment of small-cell anaplastic carcinoma of the lung.

Authors:  H S Jensen; H H Hansen; P Dombernowsky
Journal:  Cancer Chemother Pharmacol       Date:  1980       Impact factor: 3.333

6.  Disposition of orally administered 14C-prednimustine in cancer patients.

Authors:  R C Gaver; G Deeb; K A Pittman; B F Issell; A Mittelman; R D Smyth
Journal:  Cancer Chemother Pharmacol       Date:  1983       Impact factor: 3.333

7.  Mitozantrone and prednimustine in the treatment of advanced breast cancer--a toxic regimen with low activity.

Authors:  M E O'Brien; D M Eccles; S G Allen; G Knight; A Rodger; U Chetty; J F Smyth; R C Leonard
Journal:  Cancer Chemother Pharmacol       Date:  1991       Impact factor: 3.333

8.  Prednimustine in adult acute myeloid leukaemia.

Authors:  L Brandt; I Könyves
Journal:  Cancer Chemother Pharmacol       Date:  1979       Impact factor: 3.333

  8 in total

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