Guangli Yin1, Bofei Ma2, Bolun Zhou3, Jinglan Wu4, Ling You5, Ruiqin Xie6. 1. Department of Cardiology, the Second Hospital of Hebei Medical University, Shijiazhuang, China. yin_guangli@163.com. 2. Department of Cardiology, the Second Hospital of Hebei Medical University, Shijiazhuang, China. 18031783319@163.com. 3. Xiangya School of Medicine, Central South University, Changsha, China. zhoubolun132@gmail.com. 4. Department of Cardiology, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, China. 906678092@qq.com. 5. Department of Cardiology, the Second Hospital of Hebei Medical University, Shijiazhuang, China. 171135436@qq.com. 6. Department of Cardiology, the Second Hospital of Hebei Medical University, Shijiazhuang, China. ruiqinxiedoc@163.com.
Abstract
BACKGROUND: Catheter ablation for atrial fibrillation (AF) has been gaining popularity; however, the trend of inflammatory response markers in patients treated with different catheter ablation strategies over time and their predictability of AF recurrence remain unknown. METHODS: A total of 210 patients with AF were enrolled and grouped according to surgical mode as follows: freeze group, RF group, and freeze3D group. The subjects were tested for related indexes before and after surgery. To determine AF recurrence during follow up, 24-h ambulatory electrocardiography was performed at two, three, six, and 12 months after surgery. RESULTS: The inflammation indexes of the three groups peaked between one and three days after surgery but fell at different time points (P < .05). The recurrence rate of paroxysmal atrial fibrillation (PAF) was positively correlated with the increase in the percentage of white blood cells and neutrophils after surgery (P < .05). CONCLUSIONS: The postoperative inflammation indices peaked and fell at different time points after different catheter ablation methods. In addition, the recurrence rate of AF in patients treated with freeze3D is lower.
BACKGROUND: Catheter ablation for atrial fibrillation (AF) has been gaining popularity; however, the trend of inflammatory response markers in patients treated with different catheter ablation strategies over time and their predictability of AF recurrence remain unknown. METHODS: A total of 210 patients with AF were enrolled and grouped according to surgical mode as follows: freeze group, RF group, and freeze3D group. The subjects were tested for related indexes before and after surgery. To determine AF recurrence during follow up, 24-h ambulatory electrocardiography was performed at two, three, six, and 12 months after surgery. RESULTS: The inflammation indexes of the three groups peaked between one and three days after surgery but fell at different time points (P < .05). The recurrence rate of paroxysmal atrial fibrillation (PAF) was positively correlated with the increase in the percentage of white blood cells and neutrophils after surgery (P < .05). CONCLUSIONS: The postoperative inflammation indices peaked and fell at different time points after different catheter ablation methods. In addition, the recurrence rate of AF in patients treated with freeze3D is lower.