Jian-Han Chen1,2,3,4, Yu-Feng Wei5,6, Chung-Yen Chen7,8,5,9, Yu-Chieh Su9,10, Robert Shan Fon Tsai11, Wei-Leng Chin7,12, Ho-Shen Lee5,6. 1. Bariatric and Metabolic International Surgery Center, Department of General Surgery, E-Da Hospital, No. 1, Yida Rd., Yanchao Dist., Kaohsiung City, 824, Taiwan, Republic of China. JAMIHAN1981@gmail.com. 2. Division of General Surgery, E-Da Hospital, Kaohsiung City, Taiwan. JAMIHAN1981@gmail.com. 3. School of Medicine for Post-Baccalaureate, College of Medicine, I-Shou University, Kaohsiung, Taiwan. JAMIHAN1981@gmail.com. 4. School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan. JAMIHAN1981@gmail.com. 5. School of Medicine for Post-Baccalaureate, College of Medicine, I-Shou University, Kaohsiung, Taiwan. 6. Division of Chest Medicine, Department of Internal Medicine, E-Da Hospital, Kaohsiung, Taiwan. 7. Bariatric and Metabolic International Surgery Center, Department of General Surgery, E-Da Hospital, No. 1, Yida Rd., Yanchao Dist., Kaohsiung City, 824, Taiwan, Republic of China. 8. Division of General Surgery, E-Da Hospital, Kaohsiung City, Taiwan. 9. School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan. 10. Division of Hematology-Oncology, E-Da Hospital, Kaohsiung, Taiwan. 11. Department of Respiratory Medicine, Kaohsiung Municipal Gangshan Hospital, Kaohsiung, Taiwan. 12. Department of Family Medicine, E-Da Hospital, Kaohsiung, Taiwan.
Abstract
PURPOSE: This study aims to determine whether bariatric surgery (BS) decreases the risk of respiratory tract infections (RTIs) in obese patients. MATERIALS AND METHODS: This retrospective, population-based, matched cohort study utilized data from the Taiwan National Health Insurance Research Database. All patients 18 to 55 years of age with obesity diagnosed between 2005 and 2010 were enrolled. Patients were separated into two groups based on whether they underwent BS. Two groups were selected using 1:1 propensity score matching according to age, sex, and comorbidities. The general population was also enrolled for comparison. The primary endpoint was the incidence of RTIs, including pneumonia, influenza, and bronchitis. All patients were followed up until the end of 2013, the primary endpoint, or death. RESULTS: Compared to the non-surgery group, the BS group was at significantly lower risk for RTIs (aHR 0.432, 95% CI 0.340-0.549, p < 0.001) with shorter length of hospital stay (LOH) and lower cost. Regardless of the RTI-related mortality, pneumonia, influenza, and bronchitis rates, BS did have significant protective effects on the non-surgery group. Compared to the general population, the BS group was at higher risk for RTIs (aHR 3.601, 95% CI 2.742-4.728, p < 0.001) with similar LOH and lower cost. CONCLUSION: Patients with obesity who underwent BS were at significantly lower risk for RTIs than obese patients who did not undergo BS but were at higher risk for RTIs than the general population. BS may result in a long-term reduction of the RTI risk.
PURPOSE: This study aims to determine whether bariatric surgery (BS) decreases the risk of respiratory tract infections (RTIs) in obesepatients. MATERIALS AND METHODS: This retrospective, population-based, matched cohort study utilized data from the Taiwan National Health Insurance Research Database. All patients 18 to 55 years of age with obesity diagnosed between 2005 and 2010 were enrolled. Patients were separated into two groups based on whether they underwent BS. Two groups were selected using 1:1 propensity score matching according to age, sex, and comorbidities. The general population was also enrolled for comparison. The primary endpoint was the incidence of RTIs, including pneumonia, influenza, and bronchitis. All patients were followed up until the end of 2013, the primary endpoint, or death. RESULTS: Compared to the non-surgery group, the BS group was at significantly lower risk for RTIs (aHR 0.432, 95% CI 0.340-0.549, p < 0.001) with shorter length of hospital stay (LOH) and lower cost. Regardless of the RTI-related mortality, pneumonia, influenza, and bronchitis rates, BS did have significant protective effects on the non-surgery group. Compared to the general population, the BS group was at higher risk for RTIs (aHR 3.601, 95% CI 2.742-4.728, p < 0.001) with similar LOH and lower cost. CONCLUSION:Patients with obesity who underwent BS were at significantly lower risk for RTIs than obesepatients who did not undergo BS but were at higher risk for RTIs than the general population. BS may result in a long-term reduction of the RTI risk.
Authors: Janice K Louie; Meileen Acosta; Michael C Samuel; Robert Schechter; Duc J Vugia; Kathleen Harriman; Bela T Matyas Journal: Clin Infect Dis Date: 2011-01-04 Impact factor: 9.079
Authors: Maria C Harpsøe; Nete M Nielsen; Nina Friis-Møller; Mikael Andersson; Jan Wohlfahrt; Allan Linneberg; Ellen A Nohr; Tine Jess Journal: Am J Epidemiol Date: 2016-04-28 Impact factor: 4.897
Authors: Marina Valente; Giorgio Dalmonte; Matteo Riccò; Tarek Debs; Jean Gugenheim; Antonio Iannelli; Maria Marcantonio; Alfredo Annicchiarico; Paolo Del Rio; Gabriele Luciano Petracca; Francesco Tartamella; Federico Marchesi Journal: Obes Surg Date: 2021-03-31 Impact factor: 4.129