Literature DB >> 3298542

Inhibitory effect of a protease inhibitor, leupeptin, on the development of influenza pneumonia, mediated by concomitant bacteria.

M Tashiro, H D Klenk, R Rott.   

Abstract

The protease inhibitor leupeptin prevented multiple step replication of an influenza virus (A/swine/1976/31, H1N1) mediated by staphylococcal proteases. It also suppressed virus replication and development of fatal pneumonia in mice co-infected with the virus and Staphylococcus aureus.

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Year:  1987        PMID： 3298542     DOI： 10.1099/0022-1317-68-7-2039

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  18 in total

1.  Intraluminal proteolytic activation plays an important role in replication of type 1 reovirus in the intestines of neonatal mice.

Authors:  D M Bass; D Bodkin; R Dambrauskas; J S Trier; B N Fields; J L Wolf
Journal:  J Virol       Date:  1990-04       Impact factor: 5.103

2.  Evaluation of anti-influenza effects of camostat in mice infected with non-adapted human influenza viruses.

Authors:  M G Lee; K H Kim; K Y Park; J S Kim
Journal:  Arch Virol       Date:  1996       Impact factor: 2.574

Review 3.  The pathogenetic basis of viral tropism.

Authors:  C A Mims
Journal:  Am J Pathol       Date:  1989-09       Impact factor: 4.307

4.  Kallistatin ameliorates influenza virus pathogenesis by inhibition of kallikrein-related peptidase 1-mediated cleavage of viral hemagglutinin.

Authors:  Chia-Hsing Leu; Mei-Lin Yang; Nai-Hui Chung; Yen-Jang Huang; Yu-Chu Su; Yi-Cheng Chen; Chia-Cheng Lin; Gia-Shing Shieh; Meng-Ya Chang; Shainn-Wei Wang; Yao Chang; Julie Chao; Lee Chao; Chao-Liang Wu; Ai-Li Shiau
Journal:  Antimicrob Agents Chemother       Date:  2015-07-06       Impact factor: 5.191

5.  Proteolytic digestion of reovirus in the intestinal lumens of neonatal mice.

Authors:  D K Bodkin; M L Nibert; B N Fields
Journal:  J Virol       Date:  1989-11       Impact factor: 5.103

6.  Cleavage of influenza a virus hemagglutinin in human respiratory epithelium is cell associated and sensitive to exogenous antiproteases.

Authors:  Oleg P Zhirnov; Mine R Ikizler; Peter F Wright
Journal:  J Virol       Date:  2002-09       Impact factor: 5.103

Review 7.  Bench-to-bedside review: bacterial pneumonia with influenza - pathogenesis and clinical implications.

Authors:  Koenraad F van der Sluijs; Tom van der Poll; René Lutter; Nicole P Juffermans; Marcus J Schultz
Journal:  Crit Care       Date:  2010-04-19       Impact factor: 9.097

8.  Replication of influenza B virus in chicken embryos is suppressed by exogenous aprotinin.

Authors:  O P Zhirnov; P B Golyando; A V Ovcharenko
Journal:  Arch Virol       Date:  1994       Impact factor: 2.574

9.  A serpin shapes the extracellular environment to prevent influenza A virus maturation.

Authors:  Meike Dittmann; Hans-Heinrich Hoffmann; Margaret A Scull; Rachel H Gilmore; Kierstin L Bell; Michael Ciancanelli; Sam J Wilson; Stefania Crotta; Yingpu Yu; Brenna Flatley; Jing W Xiao; Jean-Laurent Casanova; Andreas Wack; Paul D Bieniasz; Charles M Rice
Journal:  Cell       Date:  2015-02-12       Impact factor: 41.582

10.  Linezolid has unique immunomodulatory effects in post-influenza community acquired MRSA pneumonia.

Authors:  Urvashi Bhan; Amy B Podsiad; Melissa A Kovach; Megan N Ballinger; Venkateshwar Keshamouni; Theodore J Standiford
Journal:  PLoS One       Date:  2015-01-30       Impact factor: 3.240
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