Literature DB >> 3298525

Expression of human adenosine deaminase in nonhuman primates after retrovirus-mediated gene transfer.

P W Kantoff, A P Gillio, J R McLachlin, C Bordignon, M A Eglitis, N A Kernan, R C Moen, D B Kohn, S F Yu, E Karson.   

Abstract

Primate bone marrow cells were infected with a retroviral vector carrying the genes for human adenosine deaminase (h-ADA) and bacterial neomycin resistance (neor). The infected cells were infused back into the lethally irradiated donor animals. Several monkeys fully reconstituted and were shown to express the h-ADA and neor genes at low levels in their recirculating hematopoietic cells for short periods of time.

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Year:  1987        PMID: 3298525      PMCID: PMC2188649          DOI: 10.1084/jem.166.1.219

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  23 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

2.  Gene transfer to primary normal and malignant human hemopoietic progenitors using recombinant retroviruses.

Authors:  D E Hogge; R K Humphries
Journal:  Blood       Date:  1987-02       Impact factor: 22.113

3.  Human bone marrow colony growth in agar-gel.

Authors:  B L Pike; W A Robinson
Journal:  J Cell Physiol       Date:  1970-08       Impact factor: 6.384

4.  A new sensitive method for qualitative and quantitative assay of neomycin phosphotransferase in crude cell extracts.

Authors:  B Reiss; R Sprengel; H Will; H Schaller
Journal:  Gene       Date:  1984-10       Impact factor: 3.688

5.  Structure of adenosine deaminase mRNAs from normal and adenosine deaminase-deficient human cell lines.

Authors:  G S Adrian; D A Wiginton; J J Hutton
Journal:  Mol Cell Biol       Date:  1984-09       Impact factor: 4.272

6.  Retrovirus transfer of a bacterial gene into mouse haematopoietic progenitor cells.

Authors:  A Joyner; G Keller; R A Phillips; A Bernstein
Journal:  Nature       Date:  1983 Oct 6-12       Impact factor: 49.962

7.  Isolation of high-molecular-weight DNA from mammalian cells.

Authors:  M Gross-Bellard; P Oudet; P Chambon
Journal:  Eur J Biochem       Date:  1973-07-02

8.  Introduction of new genetic material into pluripotent haematopoietic stem cells of the mouse.

Authors:  D A Williams; I R Lemischka; D G Nathan; R C Mulligan
Journal:  Nature       Date:  1984 Aug 9-15       Impact factor: 49.962

9.  Human adenosine deaminase. cDNA and complete primary amino acid sequence.

Authors:  P E Daddona; D S Shewach; W N Kelley; P Argos; A F Markham; S H Orkin
Journal:  J Biol Chem       Date:  1984-10-10       Impact factor: 5.157

10.  Prospects for human gene therapy.

Authors:  W F Anderson
Journal:  Science       Date:  1984-10-26       Impact factor: 47.728

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  28 in total

1.  A new retrovirus packaging cell for gene transfer constructed from amplified long terminal repeat-free chimeric proviral genes.

Authors:  Y Takahara; K Hamada; D E Housman
Journal:  J Virol       Date:  1992-06       Impact factor: 5.103

2.  Long-term expression of human adenosine deaminase in rhesus monkeys transplanted with retrovirus-infected bone-marrow cells.

Authors:  V W van Beusechem; A Kukler; P J Heidt; D Valerio
Journal:  Proc Natl Acad Sci U S A       Date:  1992-08-15       Impact factor: 11.205

3.  Clinical application of somatic gene therapy in inborn errors of metabolism.

Authors:  F D Ledley
Journal:  J Inherit Metab Dis       Date:  1990       Impact factor: 4.982

4.  Ectopic expression of the erythrocyte band 3 anion exchange protein, using a new avian retrovirus vector.

Authors:  S Fuerstenberg; H Beug; M Introna; K Khazaie; A Muñoz; S Ness; K Nordström; J Sap; I Stanley; M Zenke
Journal:  J Virol       Date:  1990-12       Impact factor: 5.103

5.  Expression of human adenosine deaminase in murine hematopoietic cells.

Authors:  J W Belmont; G R MacGregor; K Wager-Smith; F A Fletcher; K A Moore; D Hawkins; D Villalon; S M Chang; C T Caskey
Journal:  Mol Cell Biol       Date:  1988-12       Impact factor: 4.272

6.  Development of a high-titer retrovirus producer cell line capable of gene transfer into rhesus monkey hematopoietic stem cells.

Authors:  D M Bodine; K T McDonagh; S J Brandt; P A Ney; B Agricola; E Byrne; A W Nienhuis
Journal:  Proc Natl Acad Sci U S A       Date:  1990-05       Impact factor: 11.205

7.  Long-term expression of human adenosine deaminase in mice transplanted with retrovirus-infected hematopoietic stem cells.

Authors:  B Lim; J F Apperley; S H Orkin; D A Williams
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

8.  Long-term transplantation of canine keratinocytes made resistant to G418 through retrovirus-mediated gene transfer.

Authors:  M E Flowers; M A Stockschlaeder; F G Schuening; D Niederwieser; R Hackman; A D Miller; R Storb
Journal:  Proc Natl Acad Sci U S A       Date:  1990-03       Impact factor: 11.205

9.  Infection efficiency of T lymphocytes with amphotropic retroviral vectors is cell cycle dependent.

Authors:  G M Springett; R C Moen; S Anderson; R M Blaese; W F Anderson
Journal:  J Virol       Date:  1989-09       Impact factor: 5.103

10.  Gene transfer into hematopoietic stem cells: long-term maintenance of in vitro activated progenitors without marrow ablation.

Authors:  D Bienzle; A C Abrams-Ogg; S A Kruth; J Ackland-Snow; R F Carter; J E Dick; R M Jacobs; S Kamel-Reid; I D Dubé
Journal:  Proc Natl Acad Sci U S A       Date:  1994-01-04       Impact factor: 11.205

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