Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Effects of Cellular Senescence on Dental Follicle Cells.

Literature DB >> 32980839

Effects of Cellular Senescence on Dental Follicle Cells.

Abstract

The dental follicle is part of the tooth germ, and isolated stem cells from this tissue (dental follicle cells; DFCs) are considered, for example, for regenerative medicine and immunotherapies. However somatic stem cells can also improve pharmaceutical research. Cell proliferation is limited by the induction of senescence, which, while reducing the therapeutic potential of DFCs for cell therapy, can also be used to study aging processes at the cellular level that can be used to test anti-aging pharmaceuticals. Unfortunately, very little is known about cellular senescence in DFCs. This review presents current knowledge about cellular senescence in DFCs.

Entities: Chemical

Keywords: Dental follicle; Dental stem cells; Osteogenic differentiation; Senescence

Year: 2020 PMID： 32980839 PMCID： PMC8120660 DOI： 10.1159/000510014

Source DB: PubMed Journal: Pharmacology ISSN： 0031-7012 Impact factor: 2.547

61 in total

1. P16/p53 expression and telomerase activity in immortalized human dental pulp cells.

Authors: Obi Egbuniwe; Bernadine D Idowu; Juan M Funes; Andrew D Grant; Tara Renton; Lucy Di Silvio
Journal: Cell Cycle Date: 2011-11-15 Impact factor: 4.534

2. Dental follicle progenitor cell heterogeneity in the developing mouse periodontium.

Authors: Xianghong Luan; Yoshihiro Ito; Smit Dangaria; Thomas G H Diekwisch
Journal: Stem Cells Dev Date: 2006-08 Impact factor: 3.272

Review 3. Keeping the senescence secretome under control: Molecular reins on the senescence-associated secretory phenotype.

Authors: Nicolas Malaquin; Aurélie Martinez; Francis Rodier
Journal: Exp Gerontol Date: 2016-05-25 Impact factor: 4.032

4. A network of p73, p53 and Egr1 is required for efficient apoptosis in tumor cells.

Authors: J Yu; V Baron; D Mercola; T Mustelin; E D Adamson
Journal: Cell Death Differ Date: 2006-09-22 Impact factor: 15.828

Review 5. Molecular pathways: harnessing E2F1 regulation for prosenescence therapy in p53-defective cancer cells.

Authors: Anni Laine; Jukka Westermarck
Journal: Clin Cancer Res Date: 2014-05-01 Impact factor: 12.531

6. Wnt3a signaling induces murine dental follicle cells to differentiate into cementoblastic/osteoblastic cells via an osterix-dependent pathway.

Authors: E Nemoto; Y Sakisaka; M Tsuchiya; M Tamura; T Nakamura; S Kanaya; M Shimonishi; H Shimauchi
Journal: J Periodontal Res Date: 2015-06-12 Impact factor: 4.419

7. Characterization of the optimal culture conditions for clinical scale production of human mesenchymal stem cells.

Authors: Panagiota A Sotiropoulou; Sonia A Perez; Maria Salagianni; Constantin N Baxevanis; Michael Papamichail
Journal: Stem Cells Date: 2005-08-18 Impact factor: 6.277

Review 8. Mesenchymal stem cells derived from dental tissues vs. those from other sources: their biology and role in regenerative medicine.

Authors: G T-J Huang; S Gronthos; S Shi
Journal: J Dent Res Date: 2009-09 Impact factor: 6.116

Effects of Cellular Senescence on Dental Follicle Cells.

1. P16/p53 expression and telomerase activity in immortalized human dental pulp cells.

2. Dental follicle progenitor cell heterogeneity in the developing mouse periodontium.

Review 3. Keeping the senescence secretome under control: Molecular reins on the senescence-associated secretory phenotype.

4. A network of p73, p53 and Egr1 is required for efficient apoptosis in tumor cells.

Review 5. Molecular pathways: harnessing E2F1 regulation for prosenescence therapy in p53-defective cancer cells.

6. Wnt3a signaling induces murine dental follicle cells to differentiate into cementoblastic/osteoblastic cells via an osterix-dependent pathway.

7. Characterization of the optimal culture conditions for clinical scale production of human mesenchymal stem cells.

Review 8. Mesenchymal stem cells derived from dental tissues vs. those from other sources: their biology and role in regenerative medicine.

Review 9. p53, ROS and senescence in the control of aging.

10. Short telomeres correlate with a strong induction of cellular senescence in human dental follicle cells.

Review 1. Mechanisms during Osteogenic Differentiation in Human Dental Follicle Cells.

Review 2. Angiogenesis in Regenerative Dentistry: Are We Far Enough for Therapy?

Review 3. Dental Pulp Stem Cell-Derived Secretome and Its Regenerative Potential.

Review 4. Stem Cells and Their Derivatives-Implications for Alveolar Bone Regeneration: A Comprehensive Review.