Literature DB >> 3297842

Evidence that protein kinase C is involved in regulating glucose transport in the adipocyte.

R L Christensen, D L Shade, C B Graves, J M McDonald.   

Abstract

The role of protein kinase C in the mechanism of stimulation of glucose transport in rat adipocytes was investigated. Glucose transport was stimulated by dioleoylglycerol (DOG), tetradecanoyl phorbol acetate (TPA) and phospholipase C (PLC). Agents that inhibit protein kinase C (polymyxin B, gossypol and quercitin) also inhibited glucose transport that had been stimulated by DOG, TPA, PLC and insulin.

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Year:  1987        PMID： 3297842     DOI： 10.1016/0020-711x(87)90029-2

Source DB:  PubMed          Journal:  Int J Biochem        ISSN： 0020-711X


  5 in total

1.  Autoamplification of tumor necrosis factor-alpha: a potential mechanism for the maintenance of elevated tumor necrosis factor-alpha in male but not female obese mice.

Authors:  Jaap G Neels; Manjula Pandey; Gökhan S Hotamisligil; Fahumiya Samad
Journal:  Am J Pathol       Date:  2006-02       Impact factor: 4.307

Review 2.  Role of kinases in insulin stimulation of glucose transport.

Authors:  A Klip; A G Douen
Journal:  J Membr Biol       Date:  1989-10       Impact factor: 1.843

3.  Regulation of the GLUT1 glucose transporter in cultured myocytes: total number and subcellular distribution as determined by photoaffinity labelling.

Authors:  I M el-Kebbi; S Roser; R J Pollet; S W Cushman; C M Wilson
Journal:  Biochem J       Date:  1994-07-01       Impact factor: 3.857

4.  Predicting the three-dimensional structure of the human facilitative glucose transporter glut1 by a novel evolutionary homology strategy: insights on the molecular mechanism of substrate migration, and binding sites for glucose and inhibitory molecules.

Authors:  Alexis Salas-Burgos; Pavel Iserovich; Felipe Zuniga; Juan Carlos Vera; Jorge Fischbarg
Journal:  Biophys J       Date:  2004-08-23       Impact factor: 4.033

5.  Staurosporine inhibits phorbol 12-myristate 13-acetate- and insulin-stimulated translocation of GLUT1 and GLUT4 glucose transporters in rat adipose cells.

Authors:  H Nishimura; I A Simpson
Journal:  Biochem J       Date:  1994-08-15       Impact factor: 3.857
  5 in total

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