Literature DB >> 32978041

Cellular Senescence Variation by Metabolic and Epigenomic Remodeling.

Mitsuyoshi Nakao1, Hiroshi Tanaka2, Tomoaki Koga2.   

Abstract

Cellular senescence is a state of permanent cell cycle arrest accompanied by unique secretory actions, which influences tissue formation, tumor suppression and aging in vivo. Recent evidences suggest that metabolic and epigenomic reprogram cooperatively creates phenotypic differences of senescent cells, which may provide new clues to control aging processes.
Copyright © 2020 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  cellular senescence; epigenome; gene regulation; metabolism; senescence-associated secretory phenotype

Year:  2020        PMID： 32978041     DOI： 10.1016/j.tcb.2020.08.009

Source DB:  PubMed          Journal:  Trends Cell Biol        ISSN： 0962-8924            Impact factor:   20.808


  9 in total

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2.  Differential regulation of cerebral microvascular transcription by single and repetitive hypoxic conditioning.

Authors:  Jarrod C Harman; David A Otohinoyi; John W Reitnauer; Ann M Stowe; Jeff M Gidday
Journal:  Cond Med       Date:  2021

Review 3.  Ageing, cellular senescence and chronic kidney disease: experimental evidence.

Authors:  Huishi Tan; Jie Xu; Youhua Liu
Journal:  Curr Opin Nephrol Hypertens       Date:  2022-02-09       Impact factor: 3.416

4.  Loss of the transcription repressor ZHX3 induces senescence-associated gene expression and mitochondrial-nucleolar activation.

Authors:  Tomoka Igata; Hiroshi Tanaka; Kan Etoh; Seonghyeon Hong; Naoki Tani; Tomoaki Koga; Mitsuyoshi Nakao
Journal:  PLoS One       Date:  2022-01-27       Impact factor: 3.240

5.  Induction of senescence-associated secretory phenotype underlies the therapeutic efficacy of PRC2 inhibition in cancer.

Authors:  Liping Chu; Yuxiu Qu; Yang An; Linjun Hou; Juewan Li; Weijia Li; Gaofeng Fan; Bao-Liang Song; En Li; Liye Zhang; Wei Qi
Journal:  Cell Death Dis       Date:  2022-02-15       Impact factor: 8.469

6.  A motor neuron disease mouse model reveals a non-canonical profile of senescence biomarkers.

Authors:  Pascual Torres; Carlos Anerillas; Omar Ramírez-Núñez; Anna Fernàndez; Mario Encinas; Mònica Povedano; Pol Andrés-Benito; Isidre Ferrer; Victòria Ayala; Reinald Pamplona; Manuel Portero-Otín
Journal:  Dis Model Mech       Date:  2022-08-29       Impact factor: 5.732

Review 7.  Microglial Morphology Across Distantly Related Species: Phylogenetic, Environmental and Age Influences on Microglia Reactivity and Surveillance States.

Authors:  Dario Carvalho-Paulo; João Bento Torres Neto; Carlos Santos Filho; Thais Cristina Galdino de Oliveira; Aline Andrade de Sousa; Renata Rodrigues Dos Reis; Zaire Alves Dos Santos; Camila Mendes de Lima; Marcus Augusto de Oliveira; Nivin Mazen Said; Sinara Franco Freitas; Marcia Consentino Kronka Sosthenes; Giovanni Freitas Gomes; Ediely Pereira Henrique; Patrick Douglas Côrrea Pereira; Lucas Silva de Siqueira; Mauro André Damasceno de Melo; Cristovam Guerreiro Diniz; Nara Gyzely de Morais Magalhães; José Antonio Picanço Diniz; Pedro Fernando da Costa Vasconcelos; Daniel Guerreiro Diniz; Daniel Clive Anthony; David Francis Sherry; Dora Brites; Cristovam Wanderley Picanço Diniz
Journal:  Front Immunol       Date:  2021-06-18       Impact factor: 7.561

8.  Effects and Related Mechanisms of the Senolytic Agent ABT-263 on the Survival of Irradiated A549 and Ca9-22 Cancer Cells.

Authors:  Kota Sato; Soichiro Iwasaki; Hironori Yoshino
Journal:  Int J Mol Sci       Date:  2021-12-08       Impact factor: 5.923

Review 9.  mTOR Activity and Autophagy in Senescent Cells, a Complex Partnership.

Authors:  Angel Cayo; Raúl Segovia; Whitney Venturini; Rodrigo Moore-Carrasco; Claudio Valenzuela; Nelson Brown
Journal:  Int J Mol Sci       Date:  2021-07-29       Impact factor: 5.923
  9 in total

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