| Literature DB >> 32975585 |
Yael Lichter1, Yan Topilsky1, Philippe Taieb1, Ariel Banai1, Aviram Hochstadt1, Ilan Merdler1, Amir Gal Oz1, Jacob Vine1, Or Goren1, Barak Cohen1, Orly Sapir1, Yoav Granot1, Tomer Mann1, Shirley Friedman1, Yoel Angel1, Nimrod Adi1, Michal Laufer-Perl1, Merav Ingbir1, Yaron Arbel1, Idit Matot1, Yishay Szekely2,3.
Abstract
The original article can be found online.Entities:
Year: 2020 PMID: 32975585 PMCID: PMC7516023 DOI: 10.1007/s00134-020-06254-5
Source DB: PubMed Journal: Intensive Care Med ISSN: 0342-4642 Impact factor: 17.440
Patients stratified by clinical presentation at baseline lung ultrasound
| Parameter | Clinical gradea | |||
|---|---|---|---|---|
| Mild | Moderate | Severe | ||
| Age, years, mean ± SD | 64.2 ± 21 | 72.3 ± 13 | 72.5 ± 24 | 0.12 |
| Male gender, | 43 (57) | 21 (67) | 10 (71) | 0.43 |
| Modified early warning score, median (IQR) | 3 (1–4) | 7 (6–10) | 13 (9–16) | < 0.0001 |
| Temperature, °C, mean ± SD | 37.1 ± 0.7 | 37.4 ± 0.8 | 37.8 ± 1.3 | 0.02 |
| O2 saturation, %, mean ± SD | 96.2 ± 3 | 88.7 ± 6 | 86.0 ± 7 | < 0.0001 |
| Heart rate, beats/min, mean ± SD | 81.1 ± 15 | 85.2 ± 17 | 98.2 ± 20 | 0.005 |
| Pressor requirement, | 0 (0) | 0 (0) | 2 (13) | 0.02 |
| C-reactive protein, mg/L, mean ± SD | 49.2 ± 45 | 106 ± 65 | 162.3 ± 68 | < 0.0001 |
| 0.7 (0.3–1.1) | 1.1 (0.7–1.7) | 2.5 (1.8–3.8) | < 0.0001 | |
| Troponin-I, ng/L, median (IQR) | 8 (4–18) | 14 (7–31) | 142 (19–213) | < 0.0001 |
| Brain natriuretic peptide, pg/mL, median (IQR) | 37 (14–105) | 42 (24–197) | 75 (57–223) | 0.04 |
| Lung crepitation, | 12 (16) | 10 (32) | 4 (28) | 0.22 |
| Baseline chest X-ray | ||||
| Bilateral infiltrates, | 21 (28) | 17 (55) | 9 (64) | 0.004 |
| Lobar infiltrates, | 6 (8) | 6 (19) | 2 (14) | 0.33 |
| Pleural effusion, | 6 (8) | 7 (23) | 4 (29) | 0.04 |
| Hilar congestion, | 2 (3) | 6 (19) | 1 (7) | 0.03 |
| Baseline lung ultrasound | ||||
| Pleural effusion, | 3 (4) | 5 (16) | 1 (7) | 0.11 |
| Homogenous diffuse B-lines, | 0 (0) | 0 (0) | 0 (0) | NS |
| Pleural thickening, | 57 (73) | 30 (97) | 13 (93) | 0.009 |
| Subpleural consolidations, | 53 (71) | 27 (87) | 13 (93) | 0.04 |
| Lung ultrasound score, median (IQR) | 12 (5–18) | 19 (14–22) | 23 (16–28) | < 0.0001 |
aAt the time of baseline lung ultrasound evaluation patients were stratified to mild disease (oxygen saturation ≥ 94% at room air) in 75, moderate disease (need for non-invasive oxygen) in 31 and severe disease (need for mechanical ventilation) in 14