| Literature DB >> 32970045 |
William L Jeffries, André F Dailey, Chan Jin, Jarvis W Carter, Lamont Scales.
Abstract
During 2018, gay, bisexual, and other men who have sex with men (MSM) accounted for 69.4% of all diagnoses of human immunodeficiency virus (HIV) infection in the United States (1). Moreover, in all 42 jurisdictions with complete laboratory reporting of CD4 and viral load results,* percentages of MSM linked to care within 1 month (80.8%) and virally suppressed (viral load <200 copies of HIV RNA/mL or interpreted as undetected) within 6 months (68.3%) of diagnosis were below target during 2018 (2). African American/Black (Black), Hispanic/Latino (Hispanic), and younger MSM disproportionately experience HIV diagnosis, not being linked to care, and not being virally suppressed. To characterize trends in these outcomes, CDC analyzed National HIV Surveillance System† data from 2014 to 2018. The number of diagnoses of HIV infection among all MSM decreased 2.3% per year (95% confidence interval [CI] = 1.9-2.8). However, diagnoses did not significantly change among either Hispanic MSM or any MSM aged 13-19 years; increased 2.2% (95% CI = 1.0-3.4) and 2.0% (95% CI = 0.6-3.3) per year among Black and Hispanic MSM aged 25-34 years, respectively; and were highest in absolute count among Black MSM. Annual percentages of linkage to care within 1 month and viral suppression within 6 months of diagnosis among all MSM increased (2.9% [95% CI = 2.4-3.5] and 6.8% [95% CI = 6.2-7.4] per year, respectively). These findings, albeit promising, warrant intensified prevention efforts for Black, Hispanic, and younger MSM.Entities:
Mesh:
Year: 2020 PMID: 32970045 PMCID: PMC7727492 DOI: 10.15585/mmwr.mm6938a1
Source DB: PubMed Journal: MMWR Morb Mortal Wkly Rep ISSN: 0149-2195 Impact factor: 17.586
Diagnoses of human immunodeficiency virus (HIV) infection and linkage to medical care within 1 month of diagnosis among men who have sex with men,* by race/ethnicity and age — 33 jurisdictions, United States, 2014–2018
| Race/Ethnicity | Diagnoses, no. | EAPC¶ (95% CI) | Linkage to medical care, no. (%) | EAPC¶ (95% CI) | ||||||||
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| 2014 | 2015 | 2016 | 2017 | 2018 | 2014–2018 | 2014 | 2015 | 2016 | 2017 | 2018 | 2014–2018 | |
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| 13–19 | 574 | 613 | 593 | 600 | 584 | 0.1 (−2.4 to 2.7) | 335 (58.4) | 376 (61.3) | 388 (65.4) | 417 (69.5) | 399 (68.3) | 4.4 (1.2 to 7.8) |
| 20–24 | 2,262 | 2,163 | 2,085 | 1,861 | 1,784 | −6.0 (−7.3 to −4.7) | 1,243 (55.0) | 1,279 (59.1) | 1,326 (63.6) | 1,216 (65.3) | 1,232 (69.1) | 5.7 (3.9 to 7.6) |
| 25–34 | 2,627 | 2,731 | 2,853 | 2,872 | 2,860 | 2.2 (1.0 to 3.4) | 1,618 (61.6) | 1,685 (61.7) | 1,879 (65.8) | 1,945 (67.7) | 2,024 (70.8) | 3.8 (2.3 to 5.3) |
| 35–44 | 925 | 912 | 908 | 911 | 933 | 0.2 (−1.9 to 2.2) | 609 (65.9) | 593 (65.0) | 605 (66.6) | 641 (70.4) | 662 (71.0) | 2.3 (−0.2 to 4.9) |
| 45–54 | 624 | 618 | 583 | 520 | 509 | −5.6 (−8.0 to −3.1) | 423 (67.8) | 410 (66.4) | 387 (66.3) | 356 (68.5) | 350 (68.8) | 0.6 (−2.6 to 3.8) |
| ≥55 | 317 | 278 | 290 | 310 | 297 | −0.3 (−3.8 to 3.4) | 222 (70.1) | 184 (66.2) | 198 (68.2) | 207 (66.8) | 214 (72.1) | 0.6 (−3.6 to 5.0) |
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| 13–19 | 222 | 234 | 228 | 242 | 222 | 0.4 (−3.6 to 4.6) | 131 (59.1) | 157 (67.2) | 154 (67.5) | 156 (64.2) | 163 (73.4) | 3.8 (−1.3 to 9.3) |
| 20–24 | 1,130 | 1,170 | 1,108 | 1,027 | 995 | −3.7 (−5.5 to −1.9) | 719 (63.6) | 775 (66.2) | 763 (68.9) | 706 (68.8) | 736 (74.0) | 3.4 (1.1 to 5.8) |
| 25–34 | 2,071 | 2,100 | 2,264 | 2,226 | 2,221 | 2.0 (0.6 to 3.3) | 1,391 (67.2) | 1,433 (68.3) | 1,659 (73.2) | 1,647 (74.0) | 1,679 (75.6) | 3.2 (1.6 to 4.8) |
| 35–44 | 1,158 | 1,125 | 1,106 | 1,113 | 1,071 | −1.6 (−3.5 to 0.2) | 806 (69.6) | 806 (71.7) | 807 (73.0) | 837 (75.2) | 869 (81.1) | 3.6 (1.4 to 5.9) |
| 45–54 | 594 | 648 | 569 | 597 | 590 | −1.0 (−3.5 to 1.5) | 416 (70.0) | 463 (71.4) | 437 (76.8) | 455 (76.2) | 464 (78.7) | 3.0 (0.1 to 6.1) |
| ≥55 | 191 | 205 | 199 | 213 | 231 | 4.4 (0.0 to 9.0) | 152 (79.9) | 153 (74.4) | 151 (75.9) | 166 (78.0) | 177 (76.6) | −0.3 (−5.1 to 4.7) |
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| 13–19 | 67 | 75 | 65 | 63 | 53 | −6.0 (−13.0 to 1.5) | 39 (58.0) | 44 (58.6) | 46 (70.9) | 48 (76.3) | 43 (81.0) | 9.9 (−0.2 to 20.9) |
| 20–24 | 332 | 337 | 305 | 286 | 215 | −9.2 (−12.4 to −5.8) | 203 (61.1) | 237 (70.4) | 215 (70.4) | 209 (73.0) | 170 (79.1) | 5.6 (1.0 to 10.4) |
| 25–34 | 568 | 613 | 605 | 528 | 499 | −3.9 (−6.4 to −1.3) | 408 (71.9) | 457 (74.6) | 444 (73.3) | 405 (76.8) | 376 (75.2) | 1.2 (−1.9 to 4.4) |
| 35–44 | 313 | 269 | 278 | 259 | 216 | −7.4 (−10.8 to −3.8) | 233 (74.4) | 202 (75.1) | 218 (78.3) | 200 (77.3) | 175 (80.7) | 1.9 (−2.4 to 6.5) |
| 45–54 | 199 | 181 | 157 | 179 | 122 | −8.9 (−13.2 to −4.4) | 150 (75.3) | 138 (76.4) | 122 (78.0) | 142 (79.4) | 106 (86.4) | 3.0 (−2.5 to 8.8) |
| ≥55 | 58 | 70 | 87 | 60 | 65 | 0.5 (−6.8 to 8.3) | 37 (64.3) | 52 (74.4) | 65 (74.3) | 45 (75.9) | 54 (83.9) | 5.5 (−3.7 to 15.6) |
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| 13–19 | 105 | 97 | 121 | 121 | 115 | 4.0 (−1.9 to 10.3) | 56 (53.4) | 64 (66.0) | 79 (65.2) | 77 (63.7) | 78 (68.1) | 4.4 (−3.1 to 12.5) |
| 20–24 | 753 | 671 | 637 | 675 | 560 | −5.6 (−7.9 to −3.3) | 461 (61.2) | 451 (67.3) | 417 (65.4) | 503 (74.6) | 405 (72.2) | 4.6 (1.5 to 7.7) |
| 25–34 | 1,700 | 1,740 | 1,617 | 1,586 | 1,605 | −2.1 (−3.6 to −0.6) | 1,179 (69.3) | 1,261 (72.4) | 1,178 (72.8) | 1,154 (72.8) | 1,246 (77.6) | 2.4 (0.5 to 4.2) |
| 35–44 | 1,213 | 1,072 | 943 | 905 | 888 | −7.8 (−9.6 to −6.0) | 912 (75.2) | 809 (75.4) | 702 (74.4) | 702 (77.5) | 694 (78.2) | 1.0 (−1.2 to 3.3) |
| 45–54 | 1,178 | 1,082 | 1,034 | 888 | 791 | −9.3 (−11.1 to −7.5) | 904 (76.7) | 832 (76.9) | 824 (79.7) | 689 (77.6) | 628 (79.4) | 0.8 (−1.5 to 3.1) |
| ≥55 | 610 | 585 | 621 | 573 | 607 | −0.3 (−2.8 to 2.3) | 450 (73.9) | 450 (77.0) | 479 (77.1) | 438 (76.4) | 470 (77.4) | 0.9 (−2.0 to 3.8) |
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Abbreviations: CI = confidence interval; EAPC = estimated annual percentage change.
* Men who have sex with men were persons whose sex at birth was male and whose transmission category was either male-to-male sexual contact or male-to-male sexual contact and injection drug use.
† Data are based on residence at time of diagnosis of HIV infection. The 33 jurisdictions were Alabama, Alaska, California, District of Columbia, Georgia, Hawaii, Illinois, Indiana, Iowa, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Nebraska, New Hampshire, New Mexico, New York, North Dakota, Oregon, South Carolina, South Dakota, Tennessee, Texas, Utah, Virginia, Washington, West Virginia, Wisconsin, and Wyoming.
§ Data have been statistically adjusted by using multiple imputation to account for unknown or missing transmission category; therefore, values might not sum to column subtotals and total.
¶ EAPCs indicate the per-year change, on average, in the number of diagnoses of HIV infection or percentage linked to medical care. EAPC p-values <0.05 indicated statistically significant trends, whereas EAPC p-values ≥0.05 indicated no significant trend.
** Hispanics/Latinos might be of any race.
Viral suppression within 6 months of diagnosis among men who have sex with men,* by race/ethnicity and age — 33 jurisdictions, United States, 2014–2018
| Race/Ethnicity | No. (%) | EAPC¶ (95% CI) | ||||
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| 2014 | 2015 | 2016 | 2017 | 2018 | 2014–2018 | |
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| 13–19 | 220 (38.4) | 277 (45.2) | 304 (51.3) | 365 (60.9) | 372 (63.7) | 13.8 (9.7 to 17.9) |
| 20–24 | 865 (38.2) | 966 (44.7) | 1,064 (51.0) | 985 (52.9) | 1,085 (60.8) | 11.5 (9.3 to 13.8) |
| 25–34 | 1,134 (43.2) | 1,302 (47.7) | 1,495 (52.4) | 1,637 (57.0) | 1,764 (61.7) | 9.3 (7.5 to 11.1) |
| 35–44 | 445 (48.1) | 468 (51.4) | 494 (54.4) | 533 (58.6) | 590 (63.2) | 7.0 (4.1 to 10.0) |
| 45–54 | 313 (50.1) | 322 (52.2) | 317 (54.3) | 309 (59.4) | 303 (59.5) | 4.8 (1.2 to 8.6) |
| ≥55 | 153 (48.2) | 150 (53.9) | 151 (52.1) | 153 (49.3) | 180 (60.4) | 3.8 (−1.1 to 9.1) |
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| 13–19 | 112 (50.7) | 128 (54.5) | 127 (55.7) | 135 (55.5) | 145 (65.3) | 5.4 (−0.2 to 11.4) |
| 20–24 | 533 (47.2) | 621 (53.1) | 639 (57.7) | 641 (62.4) | 642 (64.5) | 8.1 (5.4 to 10.9) |
| 25–34 | 1,088 (52.5) | 1,200 (57.2) | 1,403 (62.0) | 1,439 (64.7) | 1,592 (71.7) | 7.7 (5.9 to 9.6) |
| 35–44 | 647 (55.9) | 687 (61.1) | 663 (60.0) | 727 (65.3) | 775 (72.3) | 6.1 (3.6 to 8.6) |
| 45–54 | 338 (56.9) | 395 (60.9) | 360 (63.2) | 384 (64.4) | 403 (68.4) | 4.3 (1.0 to 7.7) |
| ≥55 | 111 (58.0) | 121 (58.8) | 139 (69.8) | 131 (61.6) | 151 (65.4) | 2.8 (−2.6 to 8.5) |
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| 13–19 | 31 (46.0) | 35 (46.5) | 35 (53.9) | 43 (68.2) | 37 (69.6) | 13.2 (1.8 to 25.8) |
| 20–24 | 146 (44.0) | 199 (59.2) | 176 (57.7) | 188 (65.7) | 166 (77.2) | 12.7 (7.4 to 18.3) |
| 25–34 | 322 (56.7) | 393 (64.1) | 396 (65.4) | 371 (70.3) | 350 (70.1) | 5.2 (1.8 to 8.8) |
| 35–44 | 202 (64.5) | 166 (61.8) | 203 (73.0) | 192 (74.0) | 156 (72.2) | 4.2 (−0.5 to 9.1) |
| 45–54 | 119 (59.5) | 121 (66.7) | 106 (68.0) | 118 (65.7) | 95 (77.9) | 5.1 (−0.9 to 11.6) |
| ≥55 | 32 (55.2) | 43 (62.2) | 49 (56.1) | 37 (62.6) | 46 (70.5) | 5.2 (−4.9 to 16.4) |
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| 13–19 | 50 (47.7) | 56 (57.9) | 69 (57.0) | 79 (65.3) | 81 (70.7) | 9.5 (1.3 to 18.3) |
| 20–24 | 391 (51.9) | 403 (60.0) | 373 (58.6) | 450 (66.7) | 382 (68.2) | 6.8 (3.5 to 10.2) |
| 25–34 | 964 (56.7) | 1,098 (63.1) | 1,035 (64.0) | 1,058 (66.7) | 1,147 (71.4) | 5.3 (3.3 to 7.3) |
| 35–44 | 748 (61.7) | 693 (64.6) | 632 (67.0) | 620 (68.5) | 648 (73.0) | 4.0 (1.6 to 6.5) |
| 45–54 | 754 (64.1) | 708 (65.4) | 725 (70.2) | 614 (69.2) | 567 (71.6) | 2.9 (0.4 to 5.4) |
| ≥55 | 390 (64.0) | 378 (64.6) | 404 (65.0) | 397 (69.3) | 433 (71.4) | 2.9 (−0.2 to 6.2) |
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| 3,297 (59.3) | 3,335 (63.6) | 3,239 (65.1) | 3,219 (67.8) | 3,258 (71.4) | 4.4 (3.3 to 5.6) |
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Abbreviations: CI = confidence interval; EAPC = estimated annual percentage change; HIV = human immunodeficiency virus.
* Men who have sex with men were persons whose sex at birth was male and whose transmission category was either male-to-male sexual contact or male-to-male sexual contact and injection drug use.
† Data are based on residence at time of diagnosis of HIV infection. The 33 jurisdictions were Alabama, Alaska, California, District of Columbia, Georgia, Hawaii, Illinois, Indiana, Iowa, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Nebraska, New Hampshire, New Mexico, New York, North Dakota, Oregon, South Carolina, South Dakota, Tennessee, Texas, Utah, Virginia, Washington, West Virginia, Wisconsin, and Wyoming.
§ Data have been statistically adjusted by using multiple imputation to account for unknown or missing transmission category; therefore, values might not sum to column subtotals and total.
¶ EAPCs indicate the per-year change, on average, in the percentage virally suppressed. EAPC p-values <0.05 indicated statistically significant trends, whereas EAPC p-values ≥0.05 indicated no significant trend.
** Hispanics/Latinos can be of any race.