Xin Li1, Siddharth Sridhar2,3,4,5, Jasper Fuk-Woo Chan2,3,4,5,6. 1. Department of Microbiology, Queen Mary Hospital, Hong Kong Special Administrative Region. 2. Department of Clinical Microbiology and Infection Control, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong Province. 3. State Key Laboratory of Emerging Infectious Diseases. 4. Department of Microbiology, Li Ka Shing Faculty of Medicine. 5. Carol Yu Centre for Infection. 6. Hainan Medical University-The University of Hong Kong Joint Laboratory of Tropical Infectious Diseases, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
Abstract
PURPOSE OF REVIEW: The Coronavirus Disease 2019 (COVID-19) pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global health threat associated with major socioeconomic disruptions. Understanding on the transmission characteristics of SARS-CoV-2 is crucial for optimizing preventive strategies. RECENT FINDINGS: SARS-CoV-2 can be transmitted efficiently between persons through respiratory droplets and direct and indirect contact. The significance of airborne droplet nuclei in SARS-CoV-2 transmission in the community setting is less clear. SARS-CoV-2 RNA and live viral particles may also be detected in other bodily fluids. Outbreaks have been reported in families, nursing homes, markets, restaurants, churches, shipping vessels, gyms, and healthcare facilities. Nonpharmaceutical preventive measures at both the community and individual levels are essential for reducing the transmission of SARS-CoV-2. SUMMARY: Because well tolerated and effective vaccines for SARS-CoV-2 are unlikely to be widely available in the near future, there is an urgent need for finding other measures to reduce the spread of the COVID-19 pandemic. With better understanding of its transmission characteristics, practical nonpharmaceutical preventive measures remain essential to reduce SARS-CoV-2 transmission and its associated health and socioeconomic burdens.
PURPOSE OF REVIEW: The Coronavirus Disease 2019 (COVID-19) pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a global health threat associated with major socioeconomic disruptions. Understanding on the transmission characteristics of SARS-CoV-2 is crucial for optimizing preventive strategies. RECENT FINDINGS:SARS-CoV-2 can be transmitted efficiently between persons through respiratory droplets and direct and indirect contact. The significance of airborne droplet nuclei in SARS-CoV-2 transmission in the community setting is less clear. SARS-CoV-2 RNA and live viral particles may also be detected in other bodily fluids. Outbreaks have been reported in families, nursing homes, markets, restaurants, churches, shipping vessels, gyms, and healthcare facilities. Nonpharmaceutical preventive measures at both the community and individual levels are essential for reducing the transmission of SARS-CoV-2. SUMMARY: Because well tolerated and effective vaccines for SARS-CoV-2 are unlikely to be widely available in the near future, there is an urgent need for finding other measures to reduce the spread of the COVID-19 pandemic. With better understanding of its transmission characteristics, practical nonpharmaceutical preventive measures remain essential to reduce SARS-CoV-2 transmission and its associated health and socioeconomic burdens.