Literature DB >> 32969245

Neutrophil to lymphocyte ratio as a predictive biomarker for computed tomography scan use in mild traumatic brain injury.

George A Alexiou1, Georgios D Lianos2, Aggeliki Tzima1, Athanasios Sotiropoulos1, Anastasios Nasios1, Dimitris Metaxas1, Andreas Zigouris1, Jolanda Zika Rn1, Michail Mitsis2, Spyridon Voulgaris1.   

Abstract

Aim: Traumatic brain injury (TBI) is a serious health concern. We set out to investigate the role of neutrophil-to-lymphocytes ratio (NLR) at admission for predicting the need for computed tomography (CT) in mild-TBI. Materials & methods: A retrospective study of adult patients who presented with mild-TBI
Results: One hundred and thirty patients met the inclusion criteria. Seventy-four patients had positive CT-findings. The mean NLR-levels at presentations were 5.6 ± 4.8. Patients with positive CT-findings had significant higher NLR-levels. Receiver operating characteristic curve analysis was conducted and the threshold of NLR-levels for detecting the cases with positive CT-findings was 2.5, with 78.1% sensitivity and 63% specificity
Conclusion: To the best of our knowledge no previous study has assessed the value of NLR-levels for predicting the need for CT in mild-TBI.

Entities:  

Keywords:  CT; GCS; biomarkers; emergency department setting; head trauma; headache; ionizing radiation; mild traumatic brain injury; neutrophil-to-lymphocytes ratio; radiation exposure

Mesh:

Year:  2020        PMID: 32969245     DOI: 10.2217/bmm-2020-0150

Source DB:  PubMed          Journal:  Biomark Med        ISSN: 1752-0363            Impact factor:   2.851


  3 in total

1.  A Novel Blood Inflammatory Indicator for Predicting Deterioration Risk of Mild Traumatic Brain Injury.

Authors:  Xintong Ge; Luoyun Zhu; Meimei Li; Wenzhu Li; Fanglian Chen; Yongmei Li; Jianning Zhang; Ping Lei
Journal:  Front Aging Neurosci       Date:  2022-04-26       Impact factor: 5.750

2.  High Neutrophil-to-Lymphocyte Ratio Facilitates Cancer Growth-Currently Marketed Drugs Tadalafil, Isotretinoin, Colchicine, and Omega-3 to Reduce It: The TICO Regimen.

Authors:  Richard E Kast
Journal:  Cancers (Basel)       Date:  2022-10-10       Impact factor: 6.575

Review 3.  Credibility of the Neutrophil-to-Lymphocyte Count Ratio in Severe Traumatic Brain Injury.

Authors:  Dorota Siwicka-Gieroba; Wojciech Dabrowski
Journal:  Life (Basel)       Date:  2021-12-07
  3 in total

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