Adel Arezki1, Iman Sadri1, Félix Couture2, Russell Schwartz3, David-Dan Nguyen1, Ahmed S Zakaria3, Dean Elterman4, Claus Roehrborn5, Kevin McVary6, Kevin C Zorn7. 1. Faculty of Medicine, McGill University, Montreal, QC, Canada. 2. Division of Urology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada. 3. Division of Urology, Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada. 4. Division of Urology, University Health Network, University of Toronto, Toronto, ON, Canada. 5. Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA. 6. Division of Urology, Southern Illinois University School of Medicine, Springfield, IL, USA. 7. Division of Urology, Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada. zorn.chumurology@gmail.com.
Abstract
PURPOSE: In this review, we will discuss the state of the literature regarding Rezūm and opportunities for its application in the treatment of BPH. METHODS: A comprehensive review of original research on convective water vapor thermal therapy (Rezūm) was conducted. Articles related to transurethral resection of the prostate, holmium laser enucleation of the prostate, Aquablation, and greenlight photoselective vaporization of the prostate were reviewed for discussion. RESULTS: Rezūm distinguishes itself from other treatment options by its durable improvement in objective clinical outcomes such as IPSS and BPH Impact Index, while being cost-effective and versatile in its ability to treat a variety of prostate gland morphologies. This treatment option shows good lower urinary tract symptom relief, especially in small-to-moderate prostate sizes (30-80 cc). The use of convective heat transfer is unique and allows for localized treatment, avoiding damage to surrounding structures, thus providing an excellent safety profile and sexual function preservation. CONCLUSION: The current evidence on Rezūm warrants its consideration as a therapeutic alternative to transurethral surgery in selected patients.
PURPOSE: In this review, we will discuss the state of the literature regarding Rezūm and opportunities for its application in the treatment of BPH. METHODS: A comprehensive review of original research on convective water vapor thermal therapy (Rezūm) was conducted. Articles related to transurethral resection of the prostate, holmium laser enucleation of the prostate, Aquablation, and greenlight photoselective vaporization of the prostate were reviewed for discussion. RESULTS: Rezūm distinguishes itself from other treatment options by its durable improvement in objective clinical outcomes such as IPSS and BPH Impact Index, while being cost-effective and versatile in its ability to treat a variety of prostate gland morphologies. This treatment option shows good lower urinary tract symptom relief, especially in small-to-moderate prostate sizes (30-80 cc). The use of convective heat transfer is unique and allows for localized treatment, avoiding damage to surrounding structures, thus providing an excellent safety profile and sexual function preservation. CONCLUSION: The current evidence on Rezūm warrants its consideration as a therapeutic alternative to transurethral surgery in selected patients.
Authors: Claus G Roehrborn; Steven N Gange; Marc C Gittelman; Kenneth A Goldberg; Kalpesh Patel; Neal D Shore; Richard M Levin; Michael Rousseau; J Randolf Beahrs; Jed Kaminetsky; Barrett E Cowan; Christopher H Cantrill; Lance A Mynderse; James C Ulchaker; Thayne R Larson; Christopher M Dixon; Kevin T McVary Journal: J Urol Date: 2016-12-18 Impact factor: 7.450
Authors: Sascha A Ahyai; Peter Gilling; Steven A Kaplan; Rainer M Kuntz; Stephan Madersbacher; Francesco Montorsi; Mark J Speakman; Christian G Stief Journal: Eur Urol Date: 2010-06-11 Impact factor: 20.096
Authors: Kevin T McVary; Steven N Gange; Marc C Gittelman; Kenneth A Goldberg; Kalpesh Patel; Neal D Shore; Richard M Levin; Michael Rousseau; J Randolf Beahrs; Jed Kaminetsky; Barrett E Cowan; Christopher H Cantrill; Lance A Mynderse; James C Ulchaker; Thayne R Larson; Christopher M Dixon; Claus G Roehrborn Journal: J Sex Med Date: 2016-04-27 Impact factor: 3.802
Authors: Harris E Foster; Michael J Barry; Philipp Dahm; Manhar C Gandhi; Steven A Kaplan; Tobias S Kohler; Lori B Lerner; Deborah J Lightner; J Kellogg Parsons; Claus G Roehrborn; Charles Welliver; Timothy J Wilt; Kevin T McVary Journal: J Urol Date: 2018-06-11 Impact factor: 7.450