Literature DB >> 32956292

High-Risk Opioid Prescribing Trends: Prescription Drug Monitoring Program Data From 2010 to 2018.

Sarah J Ball1, Kit Simpson, Jingwen Zhang, Justin Marsden, Khosrow Heidari, William P Moran, Patrick D Mauldin, Jenna L McCauley.   

Abstract

OBJECTIVE: Deaths due to opioids have continued to increase in South Carolina, with 816 opioid-involved overdose deaths reported in 2018, a 9% increase from the prior year. The objective of the current study is to examine longitudinal trends (quarter [Q] 1 2010 through Q4 2018) of opioid prescribing volume and high-risk opioid prescribing behaviors in South Carolina using comprehensive dispensing data available in the South Carolina Prescription Drug Monitoring Program (SC PDMP).
DESIGN: Retrospective analyses of SC PDMP data were performed using general linear models to assess quarterly time trends and change in rate of each outcome Q1 2010 through Q4 2018. PARTICIPANTS: Opioid analgesic prescription fills from SC state residents between Q1 2010 and Q4 2018. MAIN OUTCOME MEASURES: High-risk prescribing behaviors included (1) opioid prescribing rate; (2) percentage of patients receiving opioids dispensed 90 or more average morphine milligram equivalents daily; (3) percentage of opioid prescribed days with overlapping opioid and benzodiazepine prescriptions; (4) rate per 100 000 residents of multiple provider episodes; and (5) percentage of patients prescribed extended release opioids who were opioid naive.
RESULTS: A total of 33 027 461 opioid prescriptions were filled by SC state residents within the time period of Q1 2010 through Q4 2018. A 41% decrease in the quarterly prescribing rate of opioids occurred from Q1 2010 to Q4 2018. The decrease in overall opioid prescribing was mirrored by significant decreases in all 4 high-risk prescribing behaviors.
CONCLUSION: PDMPs may represent the most complete data regarding the dispensing of opioid prescriptions and as such be valuable tools to inform and monitor the supply of licit opioids. Our results indicate that public health policy, legislative action, and multiple clinical interventions aimed at reducing high rates of opioid prescribing across the health care ecosystem appear to be succeeding in the state of South Carolina.
Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.

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Year:  2021        PMID: 32956292      PMCID: PMC7940459          DOI: 10.1097/PHH.0000000000001203

Source DB:  PubMed          Journal:  J Public Health Manag Pract        ISSN: 1078-4659


  31 in total

1.  High-Risk Prescribing to Medicaid Enrollees Receiving Opioid Analgesics: Individual- and County-Level Factors.

Authors:  Sara E Heins; Mark J Sorbero; Christopher M Jones; Andrew W Dick; Bradley D Stein
Journal:  Subst Use Misuse       Date:  2018-01-05       Impact factor: 2.164

2.  County-Level Opioid Prescribing in the United States, 2015 and 2017.

Authors:  Gery P Guy; Kun Zhang; Lyna Z Schieber; Randall Young; Deborah Dowell
Journal:  JAMA Intern Med       Date:  2019-04-01       Impact factor: 21.873

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5.  Emergency Department Prescription Opioids as an Initial Exposure Preceding Addiction.

Authors:  Megan M Butler; Rachel M Ancona; Gillian A Beauchamp; Cyrus K Yamin; Erin L Winstanley; Kimberly W Hart; Andrew H Ruffner; Shawn W Ryan; Richard J Ryan; Christopher J Lindsell; Michael S Lyons
Journal:  Ann Emerg Med       Date:  2016-02-11       Impact factor: 5.721

6.  Using prescription claims to detect aberrant behaviors with opioids: comparison and validation of 5 algorithms.

Authors:  Kathryn Rough; Krista F Huybrechts; Sonia Hernandez-Diaz; Rishi J Desai; Elisabetta Patorno; Brian T Bateman
Journal:  Pharmacoepidemiol Drug Saf       Date:  2018-04-24       Impact factor: 2.890

7.  High-risk use by patients prescribed opioids for pain and its role in overdose deaths.

Authors:  Jane A Gwira Baumblatt; Caleb Wiedeman; John R Dunn; William Schaffner; Leonard J Paulozzi; Timothy F Jones
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Review 8.  Understanding Risk Factors for Opioid Overdose in Clinical Populations to Inform Treatment and Policy.

Authors:  Tae Woo Park; Lewei Allison Lin; Avinash Hosanagar; Amanda Kogowski; Katie Paige; Amy S B Bohnert
Journal:  J Addict Med       Date:  2016 Nov/Dec       Impact factor: 3.702

9.  The Economic Burden of Prescription Opioid Overdose, Abuse, and Dependence in the United States, 2013.

Authors:  Curtis S Florence; Chao Zhou; Feijun Luo; Likang Xu
Journal:  Med Care       Date:  2016-10       Impact factor: 2.983

10.  Cohort Study of the Impact of High-Dose Opioid Analgesics on Overdose Mortality.

Authors:  Nabarun Dasgupta; Michele Jonsson Funk; Scott Proescholdbell; Annie Hirsch; Kurt M Ribisl; Steve Marshall
Journal:  Pain Med       Date:  2016-01       Impact factor: 3.750

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  1 in total

1.  Analysis of Access to Prescription Data Management Programs Data for Research.

Authors:  Vivian A Lee; Wilson M Compton; Jonathan D Pollock
Journal:  JAMA Netw Open       Date:  2022-06-01
  1 in total

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