Literature DB >> 32952386

Radiotherapeutic Care of Patients With Stage IV Lung Cancer with Thoracic Symptoms in the Veterans Health Administration.

Ruchika Gutt1, Sheetal Malhotra1, Drew Moghanaki1, Alice V Cheuk1, Lori Hoffman-Hogg1, Maria Kelly1, Helen Fosmire1, George Dawson1.   

Abstract

BACKGROUND: Radiotherapy plays an important role in the palliation of lung cancer, which is the second most common cancer diagnosed in the Veterans Health Administration (VHA). The American Society for Radiation Oncology (ASTRO) developed evidenced-based treatment guidelines for the management of patients with metastatic lung cancer.
METHODS: In May 2016, an electronic survey of 88 VHA radiation oncologists (ROs) was conducted to assess metastatic lung cancer management. Demographic information was obtained and 2 clinical scenarios were presented to glean opinions on dose/fractionation schemes preferred, preferences for/against concurrent chemotherapy, and use of endobronchial brachytherapy (EBB) and/or yttrium aluminum garnet (YAG) laser technology. Survey results were assessed for concordance with published ASTRO guidelines.
RESULTS: The survey response rate was 61%, with 93% of the 40 VHA radiation departments represented. Among respondents, 96% were board certified, and 90% held academic appointments. 88% were familiar with ASTRO guidelines. Preferred fractionation schemes were 20 Gy in 5 fractions (69%) and 30 Gy in 10 fractions (22%). The vast majority (98%) did not recommend concurrent chemotherapy for palliation. In the setting of bronchial obstruction with lung collapse, about half (49%) recommended EBB or YAG lung reexpansion before external beam radiotherapy. A minority of respondents use stereotactic body radiotherapy or EBB for palliation.
CONCLUSION: Most respondents demonstrated up-to-date knowledge of current evidence-based treatment guidelines. We found no distinction in clinical decisions based on demographic profiles.
Copyright © 2020 Frontline Medical Communications Inc., Parsippany, NJ, USA.

Entities:  

Year:  2020        PMID: 32952386      PMCID: PMC7497879     

Source DB:  PubMed          Journal:  Fed Pract        ISSN: 1078-4497


  16 in total

1.  Cancer incidence among patients of the U.S. Veterans Affairs Health Care System.

Authors:  Leah L Zullig; George L Jackson; Raye Anne Dorn; Dawn T Provenzale; Rebecca McNeil; Catherine M Thomas; Michael J Kelley
Journal:  Mil Med       Date:  2012-06       Impact factor: 1.437

Review 2.  Palliative thoracic radiotherapy for lung cancer: a systematic review.

Authors:  Alysa Fairchild; Kristin Harris; Elizabeth Barnes; Rebecca Wong; Stephen Lutz; Andrea Bezjak; Patrick Cheung; Edward Chow
Journal:  J Clin Oncol       Date:  2008-08-20       Impact factor: 44.544

3.  Presenting conditions of 1539 population-based lung cancer patients by cell type and stage in New Hampshire and Vermont.

Authors:  C G Chute; E R Greenberg; J Baron; R Korson; J Baker; J Yates
Journal:  Cancer       Date:  1985-10-15       Impact factor: 6.860

4.  Longitudinal analysis of 2293 NSCLC patients: a comprehensive study from the TYROL registry.

Authors:  Florian Kocher; Wolfgang Hilbe; Andreas Seeber; Andreas Pircher; Thomas Schmid; Richard Greil; Jutta Auberger; Meinhard Nevinny-Stickel; William Sterlacci; Alexandar Tzankov; Herbert Jamnig; Karin Kohler; August Zabernigg; Josef Frötscher; Wilhelm Oberaigner; Michael Fiegl
Journal:  Lung Cancer       Date:  2014-12-18       Impact factor: 5.705

5.  External irradiation versus external irradiation plus endobronchial brachytherapy in inoperable non-small cell lung cancer: a prospective randomized study.

Authors:  H Langendijk; J de Jong; M Tjwa; M Muller; G ten Velde; N Aaronson; R Lamers; B Slotman; M Wouters
Journal:  Radiother Oncol       Date:  2001-03       Impact factor: 6.280

6.  Concurrent chemotherapy and short course radiotherapy in patients with stage IIIA to IIIB non-small cell lung cancer not eligible for radical treatment: results of a randomized phase II study.

Authors:  Sergiusz Nawrocki; Maciej Krzakowski; Ewa Wasilewska-Tesluk; Dariusz Kowalski; Monika Rucinska; Rafal Dziadziuszko; Aleksander Sowa
Journal:  J Thorac Oncol       Date:  2010-08       Impact factor: 15.609

7.  A phase III study of radiotherapy with and without continuous-infusion fluorouracil as palliation for non-small-cell lung cancer.

Authors:  D Ball; J Smith; J Bishop; I Olver; S Davis; P O'Brien; D Bernshaw; G Ryan; M Millward
Journal:  Br J Cancer       Date:  1997       Impact factor: 7.640

8.  Concurrent palliative chemoradiation leads to survival and quality of life benefits in poor prognosis stage III non-small-cell lung cancer: a randomised trial by the Norwegian Lung Cancer Study Group.

Authors:  H H Strøm; R M Bremnes; S H Sundstrøm; N Helbekkmo; O Fløtten; U Aasebø
Journal:  Br J Cancer       Date:  2013-08-20       Impact factor: 7.640

9.  A Medical Research Council (MRC) randomised trial of palliative radiotherapy with two fractions or a single fraction in patients with inoperable non-small-cell lung cancer (NSCLC) and poor performance status. Medical Research Council Lung Cancer Working Party.

Authors: 
Journal:  Br J Cancer       Date:  1992-06       Impact factor: 7.640

10.  Poor prognosis patients with inoperable locally advanced NSCLC and large tumors benefit from palliative chemoradiotherapy: a subset analysis from a randomized clinical phase III trial.

Authors:  Hans H Strøm; Roy M Bremnes; Stein H Sundstrøm; Nina Helbekkmo; Ulf Aasebø
Journal:  J Thorac Oncol       Date:  2014-06       Impact factor: 15.609

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