Michael W Favoreto1, Mariniella P Madureira1, Viviane Hass2,3, Bianca M Maran4, Sibelli O Parreiras5, Christiane P F Borges6, Alessandra Reis1, Alessandro D Loguercio1. 1. Department of Restorative Dentistry, School of Dentistry, State University of Ponta Grossa, Paraná, Brazil. 2. School of Dentistry, University of Northern Paraná-UNOPAR, Paraná, Brazil. 3. School of Dentistry, University of Missouri-Kansas City, Kansas City, Missouri, USA. 4. Department of Restorative Dentistry, School of Dentistry, State University of Western Paraná, Paraná, Brazil. 5. School of Dentistry, State University of Northern Paraná, Paraná, Brazil. 6. Department of Chemistry, State University of Ponta Grossa, Paraná, Brazil.
Abstract
OBJECTIVE: This study evaluated the hydrogen peroxide (HP) penetration inside the pulp cavity and the color change of teeth submitted to the 15% carbamide peroxide (CP) nanoparticle bleaching gel at several application times. MATERIALS AND METHODS: Premolars were divided into nine groups (n = 6) according to 15% CP bleaching agents (nanoparticle and commercial) and to application times (15, 30, 45, and 60 minutes). A negative control was exposed to ultra-purified water. After a whitening procedure, the HP concentration (μg/mL) inside the pulp cavity was assessed via spectrophotometry. The color change (ΔE* and ΔE00*) was evaluated with a spectrophotometer. Data were analyzed via two-way ANOVA and Tukey (α = 0.05). RESULTS: A lower concentration of HP was detected for CP nanoparticle gel after 30 and 45 minutes of whitening procedure (P = .001). The bleaching groups promoted a higher color change (ΔE* and ΔE00*) regardless of the application time (P = .0001). CONCLUSIONS: The CP nanoparticle gel reduced HP inside the pulp cavity, and showed effective bleaching compared with CP commercial gel. CLINICAL SIGNIFICANCE: Using 15% carbamide peroxide nanoparticle bleaching gel decreased the HP penetration inside the pulp cavity and may decrease bleaching-induced tooth sensitivity in at-home bleaching.
OBJECTIVE: This study evaluated the hydrogen peroxide (HP) penetration inside the pulp cavity and the color change of teeth submitted to the 15% carbamide peroxide (CP) nanoparticle bleaching gel at several application times. MATERIALS AND METHODS: Premolars were divided into nine groups (n = 6) according to 15% CP bleaching agents (nanoparticle and commercial) and to application times (15, 30, 45, and 60 minutes). A negative control was exposed to ultra-purified water. After a whitening procedure, the HP concentration (μg/mL) inside the pulp cavity was assessed via spectrophotometry. The color change (ΔE* and ΔE00*) was evaluated with a spectrophotometer. Data were analyzed via two-way ANOVA and Tukey (α = 0.05). RESULTS: A lower concentration of HP was detected for CP nanoparticle gel after 30 and 45 minutes of whitening procedure (P = .001). The bleaching groups promoted a higher color change (ΔE* and ΔE00*) regardless of the application time (P = .0001). CONCLUSIONS: The CP nanoparticle gel reduced HP inside the pulp cavity, and showed effective bleaching compared with CP commercial gel. CLINICAL SIGNIFICANCE: Using 15% carbamide peroxide nanoparticle bleaching gel decreased the HP penetration inside the pulp cavity and may decrease bleaching-induced tooth sensitivity in at-home bleaching.
Authors: Laís G Bernardi; Michael W Favoreto; Taynara S Carneiro; Alexandra Mena-Serrano; Christiane P F Borges; Alessandra Reis; Alessandro D Loguercio Journal: Clin Oral Investig Date: 2022-07-01 Impact factor: 3.606