Miguel A Marín Gabriel1,2, Mar Reyne Vergeli3, Sonia Caserío Carbonero4, Laia Sole5, Tamara Carrizosa Molina6, Irene Rivero Calle7, Irene Cuadrado Pérez8, Blanca Álvarez Fernández9, Azul Forti Buratti10, Aurora Fernández-Cañadas Morillo11. 1. Deparment of Neonatology, Puerta de Hierro-Majadahonda University Hospital, Madrid, Spain. 2. Pediatric Deparment, Autónoma University, Madrid, Spain. 3. Deparment of Neonatology, Sant Joan de Deu University Hospital, Barcelona, Spain. 4. Deparment of Neonatology, Río Hortega University Hospital, Valladolid, Spain. 5. Deparment of Neonatology, Josep Trueta University Hospital, Girona, Spain. 6. Deparment of Neonatology, Fundación Jiménez Díaz University Hospital, Madrid, Spain. 7. Deparment of Pediatrics, Santiago de Compostela University Hospital, Santiago de Compostela, Spain. 8. Deparment of Neonatology, Getafe University Hospital, Madrid, Spain. 9. Deparment of Neonatology, Rey Juan Carlos University Hospital, Móstoles, Madrid, Spain. 10. Department of Psychiatry, Puerta de Hierro-Majadahonda University Hospital, Madrid, Spain, and. 11. Department of Obstetrics, Puerta de Hierro-Majadahonda University Hospital, Madrid, Spain.
Abstract
BACKGROUND: Our aim was to describe the clinical features of mothers with coronavirus disease 2019 (COVID-19) infection during gestation or delivery, and the potential vertical transmission. We also wish to evaluate the possible horizontal transmission after hospital discharge, by means of a follow-up of all the newborns included at 1 month of age. METHODS: This multicenter descriptive study involved 16 Spanish hospitals. We reviewed the medical records of 242 pregnant women diagnosed with COVID-19 from March 13 to May 31, 2020, when they were in their third trimester of pregnancy. They and their 248 newborn infants were monitored until the infant was 1 month old. RESULTS: Caesarean sections (C-sections) were performed on 63 (26%) women. The initial clinical symptoms were coughing (33%) and fever (29.7%). Mothers hospitalized due to COVID-19 pathology had a higher risk of ending their pregnancy via C-section (P = 0.027). Newborns whose mothers had been admitted due to their COVID-19 infection had a higher risk of premature delivery (P = 0.006). We admitted 115 (46.3%) newborn infants to the neonatal unit, of those, 87 (75.6%) were only admitted due to organizational circumstances. No infants died and no vertical or horizontal transmission was detected. Regarding type of feeding, 41.7% of the newborns received exclusive breast-feeding at discharge and 40.4% at 1 month. CONCLUSIONS: We did not detect COVID-19 transmission during delivery or throughout the first month of life in the newborns included in our study. Exclusive breast-feeding rates at discharge and at 1 month of age were lower than expected.
BACKGROUND: Our aim was to describe the clinical features of mothers with coronavirus disease 2019 (COVID-19) infection during gestation or delivery, and the potential vertical transmission. We also wish to evaluate the possible horizontal transmission after hospital discharge, by means of a follow-up of all the newborns included at 1 month of age. METHODS: This multicenter descriptive study involved 16 Spanish hospitals. We reviewed the medical records of 242 pregnant women diagnosed with COVID-19 from March 13 to May 31, 2020, when they were in their third trimester of pregnancy. They and their 248 newborn infants were monitored until the infant was 1 month old. RESULTS: Caesarean sections (C-sections) were performed on 63 (26%) women. The initial clinical symptoms were coughing (33%) and fever (29.7%). Mothers hospitalized due to COVID-19 pathology had a higher risk of ending their pregnancy via C-section (P = 0.027). Newborns whose mothers had been admitted due to their COVID-19infection had a higher risk of premature delivery (P = 0.006). We admitted 115 (46.3%) newborn infants to the neonatal unit, of those, 87 (75.6%) were only admitted due to organizational circumstances. No infantsdied and no vertical or horizontal transmission was detected. Regarding type of feeding, 41.7% of the newborns received exclusive breast-feeding at discharge and 40.4% at 1 month. CONCLUSIONS: We did not detect COVID-19 transmission during delivery or throughout the first month of life in the newborns included in our study. Exclusive breast-feeding rates at discharge and at 1 month of age were lower than expected.
Authors: Tina L Schuh; Leena B Mithal; Sara Naureckas; Emily S Miller; Craig F Garfield; Malika D Shah Journal: J Perinat Med Date: 2021-12-10 Impact factor: 2.716
Authors: Sara Vigil-Vázquez; Itziar Carrasco-García; Alicia Hernanz-Lobo; Ángela Manzanares; Alba Pérez-Pérez; Javier Toledano-Revenga; Mar Muñoz-Chapuli; Lara Mesones-Guerra; Andrea Martínez-Lozano; Beatriz Pérez-Seoane; Elena Márquez-Isidro; Olga Sanz-Asín; Gloria Caro-Chinchilla; Marta Sardá-Sánchez; Álvaro Solaz-García; Juan López-Carnero; Marta Pareja-León; Mónica Riaza-Gómez; María Concepción Ortiz-Barquero; Juan Antonio León-Luis; María Jesús Fernández-Aceñero; María Ángeles Muñoz-Fernández; Pilar Catalán-Alonso; Patricia Muñoz-García; Manuel Sánchez-Luna; María Luisa Navarro-Gómez Journal: Pediatr Infect Dis J Date: 2022-05-06 Impact factor: 3.806