Nicole T Shen1, Jeremy Bray2, Nabeel A Wahid3, Michael Raver1, Nicholas Hutchison1, Robert S Brown1, Bruce R Schackman4. 1. From the, Division of Gastroenterology and Hepatology, (NTS, MR, NH, RSB), Weill Cornell Medicine, New York, New York. 2. Department of Economics, (JB), University of North Carolina at Greensboro, Greensboro, North Carolina. 3. Department of Internal Medicine, (NAW), Weill Cornell Medicine/New York-Presbyterian Hospital, New York, New York. 4. Department of Healthcare Policy & Research, (BRS), Weill Cornell Medicine, New York, New York.
Abstract
BACKGROUND: Alcohol-related liver disease (ALD) is a leading indication for liver transplantation. METHODS: State consumption of spirits, wine, and beer was determined from published sources. Excise and ad valorem alcohol taxes of spirits, wine, and beer were calculated following standard practices and correlated using multiple logistic regression models to 2002 to 2015 ALD transplant listing data from the United Network for Organ Sharing database. RESULTS: 21.22% (29,161/137,440) of transplant listings were for ALD. Increased consumption of spirits was associated with increased ALD transplant listings (odds ratio [OR]: 1.67; 95% CI: 1.12 to 2.49, p = 0.01), but wine and beer consumption did not have a statistically significant association with ALD transplant listings. Spirits excise taxes on- and off-premise were inversely associated with ALD transplant listing (OR: 0.79 and 0.82, respectively, both p < 0.02). Beer and wine taxes were not significantly associated with ALD transplant listings. CONCLUSIONS: Transplant listings for ALD are directly associated with spirit consumption and inversely associated with spirits excise taxes. These findings suggest a possible public health benefit of increasing excise taxes for spirits.
BACKGROUND:Alcohol-related liver disease (ALD) is a leading indication for liver transplantation. METHODS: State consumption of spirits, wine, and beer was determined from published sources. Excise and ad valorem alcohol taxes of spirits, wine, and beer were calculated following standard practices and correlated using multiple logistic regression models to 2002 to 2015 ALD transplant listing data from the United Network for Organ Sharing database. RESULTS: 21.22% (29,161/137,440) of transplant listings were for ALD. Increased consumption of spirits was associated with increased ALD transplant listings (odds ratio [OR]: 1.67; 95% CI: 1.12 to 2.49, p = 0.01), but wine and beer consumption did not have a statistically significant association with ALD transplant listings. Spirits excise taxes on- and off-premise were inversely associated with ALD transplant listing (OR: 0.79 and 0.82, respectively, both p < 0.02). Beer and wine taxes were not significantly associated with ALD transplant listings. CONCLUSIONS: Transplant listings for ALD are directly associated with spirit consumption and inversely associated with spirits excise taxes. These findings suggest a possible public health benefit of increasing excise taxes for spirits.
Authors: Nicole T Shen; Ashley Wu; Karen Farrell; Amanda Ivatorov; Enad Dawod; Michael Raver; Nicholas Russo; Laura Robbins; Monika Safford; Robert S Brown Journal: Liver Transpl Date: 2019-09-25 Impact factor: 5.799
Authors: Timothy S Naimi; Ziming Xuan; Vishnudas Sarda; Scott E Hadland; Marlene C Lira; Monica H Swahn; Robert B Voas; Timothy C Heeren Journal: JAMA Intern Med Date: 2018-07-01 Impact factor: 21.873
Authors: Bridget F Grant; S Patricia Chou; Tulshi D Saha; Roger P Pickering; Bradley T Kerridge; W June Ruan; Boji Huang; Jeesun Jung; Haitao Zhang; Amy Fan; Deborah S Hasin Journal: JAMA Psychiatry Date: 2017-09-01 Impact factor: 21.596