| Literature DB >> 32944612 |
Marie Dumont1, Daniele Fachinetti1.
Abstract
The overall structure and composition of human centromeres have been well reported, but how these elements vary between individual chromosomes and influence the chromosome-specific behavior during mitosis remains untested. In our study, we discover the existence of heterogeneity of centromeric DNA features that dictates the chromosome segregation fidelity during mitosis.Entities:
Keywords: Centromere; aneuploidy; cell division
Year: 2020 PMID: 32944612 PMCID: PMC7469452 DOI: 10.1080/23723556.2020.1742063
Source DB: PubMed Journal: Mol Cell Oncol ISSN: 2372-3556