Literature DB >> 32943426

New trends in cellular therapy.

Hideyuki Okano1,2, Doug Sipp3,2,4,5.   

Abstract

Regenerative therapies, including both gene and cellular therapies, aim to induce regeneration of cells, tissues and organs and restore their functions. In this short Spotlight, we summarize the latest advances in cellular therapies using pluripotent stem cells (PSCs), highlighting the current status of clinical trials using induced (i)PSC-derived cells. We also discuss the different cellular products that might be used in clinical studies, and consider safety issues and other challenges in iPSC-based cell therapy.
© 2020. Published by The Company of Biologists Ltd.

Keywords:  Cardiomyopathy; Diabetes; Parkinson's disease; Pluripotent stem cells; Regenerative therapy

Mesh：

Year:  2020        PMID： 32943426     DOI： 10.1242/dev.192567

Source DB:  PubMed          Journal:  Development        ISSN： 0950-1991            Impact factor:   6.868


  6 in total

Review 1.  Clinical Development of Regenerative Medicine Targeted for Intervertebral Disc Disease.

Authors:  Daisuke Sakai; Jordy Schol; Masahiko Watanabe
Journal:  Medicina (Kaunas)       Date:  2022-02-10       Impact factor: 2.430

2.  Correlation Between Genetic Abnormalities in Induced Pluripotent Stem Cell-Derivatives and Abnormal Tissue Formation in Tumorigenicity Tests.

Authors:  Takako Yamamoto; Yoji Sato; Satoshi Yasuda; Masayuki Shikamura; Takashi Tamura; Chiemi Takenaka; Naoko Takasu; Masaki Nomura; Hiromi Dohi; Masayo Takahashi; Michiko Mandai; Yonehiro Kanemura; Masaya Nakamura; Hideyuki Okano; Shin Kawamata
Journal:  Stem Cells Transl Med       Date:  2022-05-27       Impact factor: 7.655

3.  Homologous Recombination-Enhancing Factors Identified by Comparative Transcriptomic Analyses of Pluripotent Stem Cell of Human and Common Marmoset.

Authors:  Sho Yoshimatsu; Mayutaka Nakajima; Emi Qian; Tsukasa Sanosaka; Tsukika Sato; Hideyuki Okano
Journal:  Cells       Date:  2022-01-21       Impact factor: 6.600

Review 4.  Advances in hPSC expansion towards therapeutic entities: A review.

Authors:  Shelly E Tannenbaum; Benjamin E Reubinoff
Journal:  Cell Prolif       Date:  2022-05-31       Impact factor: 8.755

5.  The Anterior Eye Chamber as a Visible Medium for In Vivo Tumorigenicity Tests.

Authors:  Emi Inagaki; Eri Arai; Shin Hatou; Tomoko Sayano; Hiroko Taniguchi; Kazuno Negishi; Yae Kanai; Yasunori Sato; Hideyuki Okano; Kazuo Tsubota; Shigeto Shimmura
Journal:  Stem Cells Transl Med       Date:  2022-08-23       Impact factor: 7.655

Review 6.  Diabetes Mellitus Is a Chronic Disease that Can Benefit from Therapy with Induced Pluripotent Stem Cells.

Authors:  Felipe Arroyave; Diana Montaño; Fernando Lizcano
Journal:  Int J Mol Sci       Date:  2020-11-18       Impact factor: 5.923
  6 in total

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