Literature DB >> 32940939

Early detection of cerebral palsy in high-risk infants: Translation of evidence into practice in an Australian hospital.

Arrabella R King1, Catherine Machipisa2, Francyne Finlayson2, Michael C Fahey1, Iona Novak3,4, Atul Malhotra1,5,6.   

Abstract

AIM: The early diagnosis of cerebral palsy (CP) allows children timely access to early intervention. In 2018, Monash Children's Hospital established an Early Neurodevelopment Clinic based upon evidence-based guidelines for the early diagnosis of CP in high-risk infants. In this study, we aimed to characterise the infants presenting to the clinic and determine the rate of CP diagnosis.
METHODS: This study analysed data from infants attending the Early Neurodevelopment Clinic between May 2019 and April 2020. Infants at high-risk for CP attended the clinic at 3 months corrected age. Neuroimaging reports were reviewed, and a Prechtl's General Movement Assessment and Hammersmith Infant Neurological Examination were performed. Infants were diagnosed as having typical development, delayed development, high-risk of CP or CP at the time of clinic attendance and referred on to the appropriate pathway.
RESULTS: Ninety-six high-risk infants attended the clinic over the 1 year study period. Sixty-eight (71%) infants were extremely preterm or extremely low birthweight, and 28 (29%) were infants at born at older gestation with evidence of moderate to severe brain injury. Nine (9.6%) infants received a CP diagnosis and 12 (12.5%) were considered high-risk of CP. All infants with CP or high-risk of CP were referred to the Victorian Paediatric Rehabilitation Service.
CONCLUSIONS: It is feasible to implement the early CP diagnosis guidelines into a high-risk infant follow-up clinic. Implementation of the guidelines allows for early diagnosis of CP and appropriate referral of high-risk infants.
© 2020 Paediatrics and Child Health Division (The Royal Australasian College of Physicians).

Entities:  

Keywords:  Hammersmith infant neurological examination; follow-up; general movement; neuroimaging

Mesh:

Year:  2020        PMID: 32940939     DOI: 10.1111/jpc.15191

Source DB:  PubMed          Journal:  J Paediatr Child Health        ISSN: 1034-4810            Impact factor:   1.954


  4 in total

Review 1.  Early Diagnosis of Cerebral Palsy in Low- and Middle-Income Countries.

Authors:  Arrabella R King; Mahmudul Hassan Al Imam; Sarah McIntyre; Catherine Morgan; Gulam Khandaker; Nadia Badawi; Atul Malhotra
Journal:  Brain Sci       Date:  2022-04-23

2.  Deep learning-based quantitative analyses of spontaneous movements and their association with early neurological development in preterm infants.

Authors:  Hyun Iee Shin; Hyung-Ik Shin; Moon Suk Bang; Don-Kyu Kim; Seung Han Shin; Ee-Kyung Kim; Yoo-Jin Kim; Eun Sun Lee; Seul Gi Park; Hye Min Ji; Woo Hyung Lee
Journal:  Sci Rep       Date:  2022-02-24       Impact factor: 4.379

3.  Neonatal Neuroimaging in Neonatal Intensive Care Graduates Who Subsequently Develop Cerebral Palsy.

Authors:  Malcolm R Battin; Sîan A Williams; Anna Mackey; Woroud Alzaher; Alexandra Sorhage; N Susan Stott
Journal:  J Clin Med       Date:  2022-03-28       Impact factor: 4.241

4.  Assessing the Utility of Neonatal Screening Assessments in Early Diagnosis of Cerebral Palsy in Preterm Infants.

Authors:  Rebecca Connors; Vathana Sackett; Catherine Machipisa; Kenneth Tan; Pramod Pharande; Lindsay Zhou; Atul Malhotra
Journal:  Brain Sci       Date:  2022-06-28
  4 in total

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