Literature DB >> 32939857

Management of acute type A aortic dissection during COVID-19 outbreak: Experience from Anzhen.

Chen-Han Zhang1, Wei-Guo Ma1, Yong-Liang Zhong1, Yi-Peng Ge1, Cheng-Nan Li1, Zhi-Yu Qiao1, Yong-Min Liu1, Jun-Ming Zhu1, Li-Zhong Sun1.   

Abstract

OBJECTIVES: We seek to report our management protocol and early outcomes of acute type A aortic dissection (ATAAD) repair during the early phase of coronavirus disease 2019 (COVID-19).
METHODS: From January 23 to April 30, 2020, we performed ATAAD repair for 33 patients, including three with pregnancy-related TAADs. Confirmation of COVID-19 depended on the results of two nucleic acid tests and pulmonary computed tomography scan. Based on testing results and hemodynamic stability, patients were triaged to an isolated intensive care unit or negative pressure operating room for emergency surgery.
RESULTS: Mean age 50.2 ± 13.3 years and 20 were male (60.1%) and 8 patients were febrile (>37.3°C; 24.2%) and 17 were lymphopenic (51.5%). No patient was excluded from COVID-19 infection preoperatively. Extensive aortic repair with total arch replacement (TAR) was performed in 24 (72.7%), and limited proximal repair in 9 patients (27.3%). Cardiopulmonary bypass and cross-clamp times averaged 177 ± 34 and 88 ± 20 min for TAR, and 150 ± 30 and 83 ± 18 min for hemiarch, respectively. The mean operation time was 410 ± 68.3 min. Operative mortality was 6.1% (2/33). Complications included reintubation in four (12.1%), acute kidney failure in two (6.1%), and cerebral infarction in one (3.0%). No paraplegia nor re-exploration for bleeding occurred. COVID-19 was excluded in 100% eventually. No nosocomial infection occurred. Nor did any patient/surgical staff develop fever or test positive during the study period.
CONCLUSIONS: The results of this study show that our management protocol based on testing results and hemodynamic stability in patients with ATAAD during the COVID-19 pandemic was effective and achieved favorable early surgical outcomes.
© 2020 Wiley Periodicals LLC.

Entities:  

Keywords:  COVID-19; aortic dissection; mortality; nosocomial infection; outcomes; surgery

Year:  2020        PMID: 32939857     DOI: 10.1111/jocs.15041

Source DB:  PubMed          Journal:  J Card Surg        ISSN: 0886-0440            Impact factor:   1.620


  2 in total

1.  Commentary: "How to Slay the Aortic Dissection Beast in a COVID-19 World".

Authors:  Subhasis Chatterjee; Joseph S Coselli; Daniel T Engelman
Journal:  Semin Thorac Cardiovasc Surg       Date:  2021-02-16

2.  Commentary: Whether it's the best of times or the worst of times, it's the only time we've got.

Authors:  Tomasz A Timek
Journal:  JTCVS Open       Date:  2020-12-29
  2 in total

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