Literature DB >> 32939068

A submicrometre silicon-on-insulator resonator for ultrasound detection.

Rami Shnaiderman1,2, Georg Wissmeyer3,4, Okan Ülgen3,4, Qutaiba Mustafa3,4, Andriy Chmyrov3,4, Vasilis Ntziachristos5,6.   

Abstract

Ultrasound detectors use high-frequency sound waves to image objects and measure distances, but the resolution of these readings is limited by the physical dimensions of the detecting element. Point-like broadband ultrasound detection can greatly increase the resolution of ultrasonography and optoacoustic (photoacoustic) imaging1,2, but current ultrasound detectors, such as those used for medical imaging, cannot be miniaturized sufficiently. Piezoelectric transducers lose sensitivity quadratically with size reduction3, and optical microring resonators4 and Fabry-Pérot etalons5 cannot adequately confine light to dimensions smaller than about 50 micrometres. Micromachining methods have been used to generate arrays of capacitive6 and piezoelectric7 transducers, but with bandwidths of only a few megahertz and dimensions exceeding 70 micrometres. Here we use the widely available silicon-on-insulator technology to develop a miniaturized ultrasound detector, with a sensing area of only 220 nanometres by 500 nanometres. The silicon-on-insulator-based optical resonator design provides per-area sensitivity that is 1,000 times higher than that of microring resonators and 100,000,000 times better than that of piezoelectric detectors. Our design also enables an ultrawide detection bandwidth, reaching 230 megahertz at -6 decibels. In addition to making the detectors suitable for manufacture in very dense arrays, we show that the submicrometre sensing area enables super-resolution detection and imaging performance. We demonstrate imaging of features 50 times smaller than the wavelength of ultrasound detected. Our detector enables ultra-miniaturization of ultrasound readings, enabling ultrasound imaging at a resolution comparable to that achieved with optical microscopy, and potentially enabling the development of very dense ultrasound arrays on a silicon chip.

Entities:  

Year:  2020        PMID: 32939068     DOI: 10.1038/s41586-020-2685-y

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  11 in total

Review 1.  Practical review on photoacoustic computed tomography using curved ultrasound array transducer.

Authors:  Jinge Yang; Seongwook Choi; Chulhong Kim
Journal:  Biomed Eng Lett       Date:  2021-12-19

2.  Acoustics at the nanoscale (nanoacoustics): A comprehensive literature review.: Part I: Materials, devices and selected applications.

Authors:  Chang Peng; Mengyue Chen; James B Spicer; Xiaoning Jiang
Journal:  Sens Actuators A Phys       Date:  2021-06-17       Impact factor: 3.407

Review 3.  Ultrasound-Responsive Systems as Components for Smart Materials.

Authors:  Athanasios G Athanassiadis; Zhichao Ma; Nicolas Moreno-Gomez; Kai Melde; Eunjin Choi; Rahul Goyal; Peer Fischer
Journal:  Chem Rev       Date:  2021-11-12       Impact factor: 60.622

Review 4.  Towards controlled drug delivery in brain tumors with microbubble-enhanced focused ultrasound.

Authors:  Scott Schoen; M Sait Kilinc; Hohyun Lee; Yutong Guo; F Levent Degertekin; Graeme F Woodworth; Costas Arvanitis
Journal:  Adv Drug Deliv Rev       Date:  2021-11-18       Impact factor: 15.470

Review 5.  Optical ultrasound sensors for photoacoustic imaging: a narrative review.

Authors:  Bo Fu; Yuan Cheng; Ce Shang; Jing Li; Gang Wang; Chenghong Zhang; Jingxuan Sun; Jianguo Ma; Xunming Ji; Boqu He
Journal:  Quant Imaging Med Surg       Date:  2022-02

6.  Massively parallel functional photoacoustic computed tomography of the human brain.

Authors:  Shuai Na; Jonathan J Russin; Li Lin; Xiaoyun Yuan; Peng Hu; Kay B Jann; Lirong Yan; Konstantin Maslov; Junhui Shi; Danny J Wang; Charles Y Liu; Lihong V Wang
Journal:  Nat Biomed Eng       Date:  2021-05-31       Impact factor: 29.234

Review 7.  Advanced high resolution three-dimensional imaging to visualize the cerebral neurovascular network in stroke.

Authors:  Chudai Zeng; Zhuohui Chen; Haojun Yang; Yishu Fan; Lujing Fei; Xinghang Chen; Mengqi Zhang
Journal:  Int J Biol Sci       Date:  2022-01-01       Impact factor: 6.580

8.  Silicon-photonics acoustic detector for optoacoustic micro-tomography.

Authors:  Yoav Hazan; Ahiad Levi; Michael Nagli; Amir Rosenthal
Journal:  Nat Commun       Date:  2022-03-18       Impact factor: 14.919

Review 9.  The Recent Progress of MEMS/NEMS Resonators.

Authors:  Lei Wei; Xuebao Kuai; Yidi Bao; Jiangtao Wei; Liangliang Yang; Peishuai Song; Mingliang Zhang; Fuhua Yang; Xiaodong Wang
Journal:  Micromachines (Basel)       Date:  2021-06-19       Impact factor: 2.891

10.  Perspective on fast-evolving photoacoustic tomography.

Authors:  Junjie Yao; Lihong V Wang
Journal:  J Biomed Opt       Date:  2021-06       Impact factor: 3.170

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