| Literature DB >> 32938733 |
Laura S Wilkendorf1, Edmée Bowles1, Jochem B Buil2,3, Henrich A L van der Lee1,3, Brunella Posteraro4,5, Maurizio Sanguinetti4,6, Paul E Verweij1,3.
Abstract
Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS)-based species identification has found its place in many clinical routine diagnostic laboratories over the past years, allowing significantly reduced turnaround times and high-precision results. With regard to MALDI-TOF MS for filamentous fungi, here, we discuss different approaches for sample processing and growth conditions before analysis. In particular, we review the performances of different commercially available databases as well as the potential of complementary (self-constructed) in-house databases.Keywords: Biotyper; Bruker; MALDI-TOF MS; Vitek; filamentous fungi; identification; in-house database
Year: 2020 PMID: 32938733 PMCID: PMC7685878 DOI: 10.1128/JCM.01263-20
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948