Literature DB >> 32938349

Role of Novel Drug Delivery Systems in Coronavirus Disease-2019 (COVID-19): Time to Act Now.

Neeraj Mittal1, Varun Garg2, Sanjay Kumar Bhadada1, Om Prakash Katare3.   

Abstract

The Coronavirus disease 2019 (COVID-19) has found its roots from Wuhan (China). COVID-19 is caused by a novel coronavirus SARS-CoV2, previously named as 2019-nCoV. It has spread across the globe and was declared as a pandemic by the World Health Organization (WHO) on 11th March, 2020. Currently, there is no standard drug or vaccine available for the treatment, therefore, repurposing of existing drugs is the only solution. Novel Drug Delivery Systems (NDDS) will be boon for the repurposing of drugs. The role of various NDDS in repurposing of existing drugs for the treatment of various viral diseases and their relevance in COVID-19 has been discussed in this paper. It focuses on the currently ongoing research in the implementation of NDDS in COVID-19. Moreover, it describes the role of NDDS in vaccine development for COVID-19. This paper also emphasizes how NDDS will help to develop the improved delivery systems (dosage forms) of existing therapeutic agents and also explore the new insights to find out the void spaces for potential targeted delivery. Therefore, in these tough times, NDDS and nanotechnology can be a safeguard to humanity. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Entities:  

Keywords:  Anti-viral; COVID-19; nanoparticles; novel drug delivery system; repurposing; vaccine

Year:  2021        PMID: 32938349     DOI: 10.2174/1567201817666200916090710

Source DB:  PubMed          Journal:  Curr Drug Deliv        ISSN: 1567-2018            Impact factor:   2.565


  2 in total

1.  Niclosamide-Clay Intercalate Coated with Nonionic Polymer for Enhanced Bioavailability toward COVID-19 Treatment.

Authors:  Seungjin Yu; Huiyan Piao; N Sanoj Rejinold; Geunwoo Jin; Goeun Choi; Jin-Ho Choy
Journal:  Polymers (Basel)       Date:  2021-03-26       Impact factor: 4.329

Review 2.  Nucleic Acid Delivery with Red-Blood-Cell-Based Carriers.

Authors:  Giulia Della Pelle; Nina Kostevšek
Journal:  Int J Mol Sci       Date:  2021-05-17       Impact factor: 5.923

  2 in total

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