Literature DB >> 32937281

Development of differentiation modulators and targeted agents for treating neuroblastoma.

Zegao Jin1, Yang Lu1, Yizhe Wu1, Jinxin Che2, Xiaowu Dong3.   

Abstract

Neuroblastoma (NB) is one of the most common pediatric malignancies. Easy metastasis, poor prognosis, and a high degree of heterogeneity of NB hinder its successful treatment. Several different therapeutic strategies have been developed to overcome these problems, including differentiation and targeted therapy. In this review, we summarize the recent development of differentiation modulators and targeted agents for treating NB. Several promising targets of NB were also discussed.
Copyright © 2020 Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  Differentiation therapy; Neuroblastoma; Targeted therapy

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Year:  2020        PMID： 32937281     DOI： 10.1016/j.ejmech.2020.112818

Source DB:  PubMed          Journal:  Eur J Med Chem        ISSN： 0223-5234            Impact factor:   6.514


  2 in total

1.  Single-cell landscape analysis reveals distinct regression trajectories and novel prognostic biomarkers in primary neuroblastoma.

Authors:  Qingqing Liu; Zhenni Wang; Yan Jiang; Fengling Shao; Yue Ma; Mingzhao Zhu; Qing Luo; Yang Bi; Lijian Cao; Liang Peng; Jianwu Zhou; Zhenzhen Zhao; Xiaobin Deng; Tong-Chuan He; Shan Wang
Journal:  Genes Dis       Date:  2022-02-04

2.  Quisinostat mediated autophagy is associated with differentiation in neuroblastoma SK-N-SH cells.

Authors:  Vamsi Krishna Kommalapati; Dinesh Kumar; Anjana Devi Tangutur
Journal:  Mol Biol Rep       Date:  2021-06-14       Impact factor: 2.316
  2 in total

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