| Literature DB >> 32936502 |
Bin Wang1, Yihang Li1, Jia Hao Pang1, Kohei Watanabe2, Ryo Takita2, Shunsuke Chiba1.
Abstract
A protocol for regio-controlled hydromagnesiation of 1,3-enynes was developed using magnesium hydride that is generated in situ by solvothermal treatment of sodium hydride (NaH) and magnesium iodide (MgI2 ) in THF. The resulting allenylmagnesium species could be converted into tri- and tetra-substituted allenes by subsequent treatment with various carbon- and silicon-based electrophiles with the aid of CuCN as a catalyst.Entities:
Keywords: allenes; enynes; hydromagnesiation; magnesium hydride; sodium hydride
Year: 2020 PMID： 32936502 DOI： 10.1002/anie.202012027
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336