Probucol Quantitative Regression Swedish Trial: new angiographic technique to measure atheroma volume of the femoral artery.

The Probucol Quantitative Regression Swedish Trial is studying the development of atherosclerosis in hyperlipidemic patients through the use of digitized femoral arteriographic examinations. In a 20-cm segment of the femoral artery, cross-sectional areas are calculated using an algorithm that was introduced by Hilal and Crawford. Changes in atheroma volume are measured in repeat arteriographic examinations. This report describes the radiologic technique, the scanning procedure and the image analysis.