Literature DB >> 32934036

The diagnostic value of 18F-FDG PET/CT in identifying the causes of fever of unknown origin.

Wan Zhu1, Wenxia Cao1, Xuting Zheng1, Xuena Li1, Yaming Li1, Baiyi Chen1, Jingping Zhang2.   

Abstract

BACKGROUND: This study investigated the clinical significance of 18F-fluorodeoxyglucose positron emission tomography / computed tomography (18F-FDG PET/CT) in identifying the causes of fever of unknown origin (FUO).
METHODS: Patients with a fever who received an 18F-FDG PET/CT examination were retrospectively selected. The means of the two groups were compared using an independent-samples t-test.
RESULTS: Among the 89 included patients, 66 were diagnosed using 18F-FDG PET/CT. The sensitivity, specificity and diagnostic accuracy of 18F-FDG PET/CT for the diagnosis of patients with FUO were 84.5%, 25.8%, and 64.0%, respectively. The detection rates of 18F-FDG PET/CT for neoplastic diseases, infectious diseases and non-infectious inflammatory diseases were 100%, 61.3%, and 75%, respectively. The difference in C-reactive protein (CRP) levels between the two groups was statistically significant.
CONCLUSIONS: 18F-FDG PET/CT has great clinical importance in diagnosing and identifying causes of FUO and improves the accuracy of FUO diagnosis when combined with serum CRP levels. © Royal College of Physicians 2020. All rights reserved.

Entities:  

Keywords:  18F-FDG PET/CT; CRP; biochemical indices; diagnostic value; fever of unknown origin

Mesh：

Substances：

Year:  2020        PMID： 32934036      PMCID： PMC7539723          DOI： 10.7861/clinmed.2020-0268

Source DB:  PubMed          Journal:  Clin Med (Lond)        ISSN： 1470-2118            Impact factor:   2.659


  25 in total

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Authors:  Motoki Takeuchi; Issa J Dahabreh; Takashi Nihashi; Mitsunaga Iwata; George M Varghese; Teruhiko Terasawa
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Authors:  Brian S Pugmire; Alexander R Guimaraes; Ruth Lim; Alison M Friedmann; Mary Huang; David Ebb; Howard Weinstein; Onofrio A Catalano; Umar Mahmood; Ciprian Catana; Michael S Gee
Journal:  World J Radiol       Date:  2016-03-28

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Authors:  Yoshie Omiya; Shintaro Ichikawa; Yoko Satoh; Utaroh Motosugi; Nobuaki Nakajima; Hiroshi Onishi
Journal:  Abdom Radiol (NY)       Date:  2018-12

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Authors:  Manuel Unger; Georgios Karanikas; Andreas Kerschbaumer; Stefan Winkler; Daniel Aletaha
Journal:  Wien Klin Wochenschr       Date:  2016-09-26       Impact factor: 1.704
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  1 in total

1.  Transformation: fighting the past or building the new?

Authors:  Anton Emmanuel
Journal:  Clin Med (Lond)       Date:  2020-09       Impact factor: 2.659
  1 in total

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