Literature DB >> 32933906

Kasabach-Merritt phenomenon with cellulitis in infant.

Ariyati Yosi1, Abdullah Afif Siregar2, Yasmine Siregar2, Widyaningsih Oentari3.   

Abstract

Kasabach-Merritt phenomenon (KMP) is consumptive coagulopathy in large vascular lesion. This condition is specific in kaposiform haemangioendothelioma (KHE) and tufted angioma, associated with high mortality rate. This condition often involves the limbs, trunk and retroperitoneum. The clinical features that are usually found are purpura, oedema, induration and ecchymosis. A boy baby aged 9 months presented with a history of violaceous tumour that appeared on his left leg at birth that became enlarged since 6 months ago that caused discrepancy between both of his legs. The patient has his left leg massaged through alternative treatment, causing it became bruised and wounded. Blood examination showed normocytic normochromic anaemia with severe thrombocytopenia and high D-dimer. The patient was diagnosed with KMP with cellulitis and treated with oral corticosteroid, propranolol and antibiotics. Diagnosis of KMP can be made through clinical and laboratory findings. Combination therapy with corticosteroid and propranolol can be considered for KMP treatment. © BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  cardiovascular medicine; dermatology

Mesh:

Year:  2020        PMID: 32933906      PMCID: PMC7493121          DOI: 10.1136/bcr-2020-235065

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  11 in total

Review 1.  Kasabach-Merritt syndrome: pathogenesis and management.

Authors:  G W Hall
Journal:  Br J Haematol       Date:  2001-03       Impact factor: 6.998

2.  Successful combination therapy of propranolol and prednisolone for a case with congenital Kasabach-Merritt syndrome.

Authors:  Kento Mizutani; Ai Umaoka; Kenshiro Tsuda; Masato Kakeda; Koji Habe; Keiichi Yamanaka; Megumi Suyama; Hitoshi Mizutani
Journal:  J Dermatol       Date:  2017-08-03       Impact factor: 4.005

Review 3.  Infantile hemangioma-mechanism(s) of drug action on a vascular tumor.

Authors:  Shoshana Greenberger; Joyce Bischoff
Journal:  Cold Spring Harb Perspect Med       Date:  2011-09       Impact factor: 6.915

4.  Consensus-derived practice standards plan for complicated Kaposiform hemangioendothelioma.

Authors:  Beth A Drolet; Cameron C Trenor; Leonardo R Brandão; Yvonne E Chiu; Robert H Chun; Roshni Dasgupta; Maria C Garzon; Adrienne M Hammill; Craig M Johnson; Brook Tlougan; Francine Blei; Michèle David; Ravindhra Elluru; Ilona J Frieden; Sheila F Friedlander; Ionela Iacobas; John N Jensen; David M King; Margaret T Lee; Stephen Nelson; Manish Patel; Elena Pope; Julie Powell; Marcia Seefeldt; Dawn H Siegel; Michael Kelly; Denise M Adams
Journal:  J Pediatr       Date:  2013-07       Impact factor: 4.406

Review 5.  Kaposiform hemangioendothelioma in children: a benign vascular tumor with multiple treatment options.

Authors:  Irene Schmid; Anne K Klenk; Monika Sparber-Sauer; Ewa Koscielniak; Rebecca Maxwell; Beate Häberle
Journal:  World J Pediatr       Date:  2018-07-27       Impact factor: 2.764

Review 6.  Kasabach-merritt syndrome.

Authors:  Sheilagh Maguiness; Lyn Guenther
Journal:  J Cutan Med Surg       Date:  2002-04-15       Impact factor: 2.092

Review 7.  Update on vascular tumors of infancy.

Authors:  Robert Sidbury
Journal:  Curr Opin Pediatr       Date:  2010-08       Impact factor: 2.856

8.  Kaposiform haemangioendothelioma: clinical features, complications and risk factors for Kasabach-Merritt phenomenon.

Authors:  Y Ji; K Yang; S Peng; S Chen; B Xiang; Z Xu; Y Li; Q Wang; C Wang; C Xia; L Li; X Liu; G Lu; G Yang; H Wu
Journal:  Br J Dermatol       Date:  2018-04-24       Impact factor: 9.302

Review 9.  Kasabach-Merritt Phenomenon: Classic Presentation and Management Options.

Authors:  Priya Mahajan; Judith Margolin; Ionela Iacobas
Journal:  Clin Med Insights Blood Disord       Date:  2017-03-16

Review 10.  Kaposiform hemangioendothelioma: current knowledge and future perspectives.

Authors:  Yi Ji; Siyuan Chen; Kaiying Yang; Chunchao Xia; Li Li
Journal:  Orphanet J Rare Dis       Date:  2020-02-03       Impact factor: 4.123

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