Literature DB >> 32928762

Thyroid Stimulating Hormone Stability in Patients Prescribed Synthetic or Desiccated Thyroid Products: A Retrospective Study.

Rolake Kuye1, Catherine Riggs2, Jordan King1, Rachel Heilmann1, Deanna Kurz1, Jessica Milchak1.   

Abstract

The purpose of this retrospective matched-cohort study was to evaluate the stability of thyroid stimulating hormone (TSH) in patients using synthetic compared with desiccated thyroid products. Patients using a thyroid product for the treatment of hypothyroidism were matched 1:1 on age, sex, race/ethnicity, and had a follow-up period of 3 years after the index date. The primary outcome was percent of in-range TSH values. Over 3 years, TSH values in both groups were in-range 79% of the time (P = 0.905). Our results showed no difference in longitudinal TSH stability between desiccated thyroid products and synthetic levothyroxine.
© 2020 Annals of Family Medicine, Inc.

Entities:  

Keywords:  desiccated thyroid; hypothyroidism; levothyroxine; stability; thyroid stimulating hormone (TSH); thyrotropin, thyroxine, thyroid (USP)

Mesh：

Substances：

Year:  2020        PMID： 32928762      PMCID： PMC7489980          DOI： 10.1370/afm.2545

Source DB:  PubMed          Journal:  Ann Fam Med        ISSN： 1544-1709            Impact factor:   5.166


  4 in total

1.  Guidelines for the treatment of hypothyroidism: prepared by the american thyroid association task force on thyroid hormone replacement.

Authors:  Jacqueline Jonklaas; Antonio C Bianco; Andrew J Bauer; Kenneth D Burman; Anne R Cappola; Francesco S Celi; David S Cooper; Brian W Kim; Robin P Peeters; M Sara Rosenthal; Anna M Sawka
Journal:  Thyroid       Date:  2014-12       Impact factor: 6.568

2.  Thyroid hormone treatment: new insights into an old therapy.

Authors:  D S Cooper
Journal:  JAMA       Date:  1989-05-12       Impact factor: 56.272

3.  Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: a randomized, double-blind, crossover study.

Authors:  Thanh D Hoang; Cara H Olsen; Vinh Q Mai; Patrick W Clyde; Mohamed K M Shakir
Journal:  J Clin Endocrinol Metab       Date:  2013-03-28       Impact factor: 5.958

4.  Clinical practice guidelines for hypothyroidism in adults: cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association.

Authors:  Jeffrey R Garber; Rhoda H Cobin; Hossein Gharib; James V Hennessey; Irwin Klein; Jeffrey I Mechanick; Rachel Pessah-Pollack; Peter A Singer; Kenneth A Woeber
Journal:  Endocr Pract       Date:  2012 Nov-Dec       Impact factor: 3.443
  4 in total
  2 in total

1.  Returning to a Patient-Centered Approach in the Management of Hypothyroidism.

Authors:  Jill Schneiderhan; Suzanna Zick
Journal:  Ann Fam Med       Date:  2020-09       Impact factor: 5.166

2.  Optimal Thyroid Hormone Replacement.

Authors:  Jacqueline Jonklaas
Journal:  Endocr Rev       Date:  2022-03-09       Impact factor: 25.261
  2 in total

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