| Literature DB >> 329280 |
B Foltmann, V B Pedersen, H Jacobsen, D Kauffman, G Wybrandt.
Abstract
The total sequence of 365 amino acid residues in bovine prochymosin is presented. Alignment with the amino acid sequence of porcine pepsinogen shows that 204 amino acid residues are common to the two zymogens. Further comparison and alignment with the amino acid sequence of penicillopepsin shows that 66 residues are located at identical positions in all three proteases. The three enzymes belong to a large group of proteases with two aspartate residues in the active center. This group forms a family derived from one common ancestor.Entities:
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Year: 1977 PMID: 329280 PMCID: PMC432162 DOI: 10.1073/pnas.74.6.2321
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205