Jozine M Ter Maaten1, Jeroen Dauw2, Pieter Martens3, Frauke Somers2, Kevin Damman4, Christoph Metalidis5, Petra Nijst2, Matthias Dupont2, Wilfried Mullens6. 1. Department of Cardiology, Ziekenhuis Oost-Limburg, Genk, Belgium; University of Groningen, Department of Cardiology, University Medical Center Groningen, Groningen, the Netherlands. 2. Department of Cardiology, Ziekenhuis Oost-Limburg, Genk, Belgium. 3. Department of Cardiology, Ziekenhuis Oost-Limburg, Genk, Belgium; Biomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, Diepenbeek, Belgium. 4. University of Groningen, Department of Cardiology, University Medical Center Groningen, Groningen, the Netherlands. 5. Department of Nephrology, Ziekenhuis Oost-Limburg, Genk, Belgium. 6. Department of Cardiology, Ziekenhuis Oost-Limburg, Genk, Belgium; Biomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, Diepenbeek, Belgium. Electronic address: wilfried.mullens@zol.be.
Abstract
BACKGROUND: Discontinuous intrarenal venous flow patterns, as assessed by renal Doppler ultrasound examination, are associated with changes in hemodynamics such as volume expansion and poorer diuretic response in patients with heart failure (HF). We aimed to study intrarenal venous and arterial flow patterns after decongestive treatment in patients with acute HF. METHODS AND RESULTS: Fifteen patients with acute HF were enrolled. Intrarenal venous and arterial flow patterns were assessed at baseline, 1 hour after administration of loop diuretics, at day 2 and day 3. Among patients hospitalized for acute HF, 13 (87%) had a discontinuous venous flow pattern at admission. After decongestive treatment, a significant improvement of the venous impedance index (P = .021) and venous discontinuity index (P = .004) was observed at day 3 compared with baseline. There was no effect on the intrarenal arterial flow patterns. CONCLUSIONS: In patients who exhibit discontinuous renal venous flow patterns hospitalized for decongestive treatment owing to acute HF led to a normalization of intrarenal venous flow to a continuous pattern.
BACKGROUND: Discontinuous intrarenal venous flow patterns, as assessed by renal Doppler ultrasound examination, are associated with changes in hemodynamics such as volume expansion and poorer diuretic response in patients with heart failure (HF). We aimed to study intrarenal venous and arterial flow patterns after decongestive treatment in patients with acute HF. METHODS AND RESULTS: Fifteen patients with acute HF were enrolled. Intrarenal venous and arterial flow patterns were assessed at baseline, 1 hour after administration of loop diuretics, at day 2 and day 3. Among patients hospitalized for acute HF, 13 (87%) had a discontinuous venous flow pattern at admission. After decongestive treatment, a significant improvement of the venous impedance index (P = .021) and venous discontinuity index (P = .004) was observed at day 3 compared with baseline. There was no effect on the intrarenal arterial flow patterns. CONCLUSIONS: In patients who exhibit discontinuous renal venous flow patterns hospitalized for decongestive treatment owing to acute HF led to a normalization of intrarenal venous flow to a continuous pattern.
Authors: Gonzalo Núñez-Marín; Rafael de la Espriella; Enrique Santas; Miguel Lorenzo; Gema Miñana; Eduardo Núñez; Vicent Bodí; Miguel González; José Luis Górriz; Clara Bonanad; Juan Sanchis; Antoni Bayés-Genís; Julio Núñez Journal: Eur Heart J Acute Cardiovasc Care Date: 2021-06-30