Nekma Meah1, Dmitri Wall2, Katherine York3, Bevin Bhoyrul4, Laita Bokhari4, Daniel Asz-Sigall5, Wilma F Bergfeld6, Regina C Betz7, Ulrike Blume-Peytavi8, Valerie Callender9, Vijaya Chitreddy4, Andrea Combalia10, George Cotsarelis11, Brittany Craiglow12, Jeff Donovan13, Samantha Eisman4, Paul Farrant14, Jack Green15, Ramon Grimalt16, Matthew Harries17, Maria Hordinsky18, Alan D Irvine19, Satoshi Itami20, Victoria Jolliffe21, Brett King22, Won-Soo Lee23, Amy McMichael24, Andrew Messenger25, Paradi Mirmirani26, Elise Olsen27, Seth J Orlow28, Bianca Maria Piraccini29, Adriana Rakowska30, Pascal Reygagne31, Janet L Roberts32, Lidia Rudnicka30, Jerry Shapiro28, Pooja Sharma4, Antonella Tosti33, Annika Vogt8, Martin Wade34, Leona Yip35, Abraham Zlotogorski36, Rodney D Sinclair4. 1. Sinclair Dermatology, East Melbourne, Victoria, Australia. Electronic address: nekma.meah@gmail.com. 2. Hair Restoration Blackrock, Ireland; National and International Skin Registry Solutions (NISR), Ireland. 3. Netcare Greenacres Hospital, Port Elizabeth, South Africa. 4. Sinclair Dermatology, East Melbourne, Victoria, Australia. 5. Dermalomas Clinic, Mexico City, Mexico. 6. Cleveland Clinic Main Campus, Cleveland, Ohio. 7. Institute of Human Genetics, University of Bonn, School of Medicine and University Hospital, Bonn, Germany. 8. Department of Dermatology, Venerology and Allergology, Clinical Research Center for Hair and Skin Science, Charité-Universitaetsmedizin Berlin, Berlin, Germany. 9. Callender Dermatology and Cosmetic Center, Glenn Dale, Maryland. 10. Department of Dermatology, Hospital Clinic de Barcelona, Barcelona, Spain. 11. Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania. 12. Dermatology Physicians of Connecticut, Farifield, Connecticut; Yale Department of Dermatology, New Haven, Connecticut. 13. Donovan Hair Clinic, Canada. 14. Brighton and Sussex University Hospitals Trust, United Kingdom. 15. Department of Dermatology, St. Vincent's Hospital, Victoria, Australia. 16. Facultat de Medicina i Ciències de la Salut, Universitat Internacional de Catalunya Josep Trueta s/n 08195 Sant Cugat del Vallès, Barcelona, Spain. 17. Centre for Dermatology Research, University of Manchester, MAHSC and NIHR Manchester, Manchester, United Kingdom; Biomedical Research Centre, Manchester, United Kingdom; The Dermatology Centre, Salford Royal NHS Foundation Trust, Manchester, United Kingdom. 18. Department of Dermatology, University of Minnesota Medical School, Minneapolis, Minnesota. 19. Clinical Medicine, Trinity College Dublin, Ireland. 20. Department of Dermatology, Oita University, Idaigaoka, Yufu City, Oita, Japan. 21. Centre for Cell Biology and Cutaneous Research, Blizard Institute, London, United Kingdom. 22. Yale School of Medicine, New Haven, Connecticut. 23. Department of Dermatology, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea. 24. Wake Forest University School of Medicine, Winston-Salem, North Carolina. 25. Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, United Kingdom. 26. Kaiser Permanente Vallejo, Department of Dermatology, California. 27. Duke Dermatology Clinic-Clinic 3K, Durham, North Carolina. 28. The Ronald O. Perelman Department of Dermatology at NYU Grossman School of Medicine, New York, New York. 29. International Relations, Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Alma Mater Studiorum University of Bologna, Dermatology Unit, Bologna, Italy. 30. Department of Dermatology, Medical University of Warsaw, Warsaw, Poland. 31. Centre de santé Sabouraud, Hôpital Saint Louis, Paris, France. 32. Northwest Dermatology Institute Portland, Portland, Oregon. 33. Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine. 34. The London Skin and Hair Clinic, London, United Kingdom. 35. Skin Partners Specialist Dermatologists, Brisbane, Queensland, Australia. 36. Department of Dermatology, Hadassah Medical Center, Hebrew University of Jerusalem, The Faculty of Medicine, Jerusalem, Israel.
Abstract
BACKGROUND: We previously reported the Alopecia Areata Consensus of Experts study, which presented results of an international expert opinion on treatments for alopecia areata. OBJECTIVE: To report the results of the Alopecia Areata Consensus of Experts international expert opinion on diagnosis and laboratory evaluation for alopecia areata. METHODS: Fifty hair experts from 5 continents were invited to participate in a 3-round Delphi process. Consensus threshold was set at greater than or equal to 66%. RESULTS: Of 148 questions, expert consensus was achieved in 82 (55%). Round 1 consensus was achieved in 10 of 148 questions (7%). Round 2 achieved consensus in 47 of 77 questions (61%). The final face-to-face achieved consensus in 25 of 32 questions (78%). Consensus was greatest for laboratory evaluation (12 of 14 questions [86%]), followed by diagnosis (11 of 14 questions [79%]) of alopecia areata. Overall, etiopathogenesis achieved the least category consensus (31 of 68 questions [46%]). LIMITATIONS: The study had low representation from Africa, South America, and Asia. CONCLUSION: There is expert consensus on aspects of epidemiology, etiopathogenesis, clinical features, diagnosis, laboratory evaluation, and prognostic indicators of alopecia areata. The study also highlights areas where future clinical research could be directed to address unresolved hypotheses in alopecia areata patient care.
BACKGROUND: We previously reported the Alopecia Areata Consensus of Experts study, which presented results of an international expert opinion on treatments for alopecia areata. OBJECTIVE: To report the results of the Alopecia Areata Consensus of Experts international expert opinion on diagnosis and laboratory evaluation for alopecia areata. METHODS: Fifty hair experts from 5 continents were invited to participate in a 3-round Delphi process. Consensus threshold was set at greater than or equal to 66%. RESULTS: Of 148 questions, expert consensus was achieved in 82 (55%). Round 1 consensus was achieved in 10 of 148 questions (7%). Round 2 achieved consensus in 47 of 77 questions (61%). The final face-to-face achieved consensus in 25 of 32 questions (78%). Consensus was greatest for laboratory evaluation (12 of 14 questions [86%]), followed by diagnosis (11 of 14 questions [79%]) of alopecia areata. Overall, etiopathogenesis achieved the least category consensus (31 of 68 questions [46%]). LIMITATIONS: The study had low representation from Africa, South America, and Asia. CONCLUSION: There is expert consensus on aspects of epidemiology, etiopathogenesis, clinical features, diagnosis, laboratory evaluation, and prognostic indicators of alopecia areata. The study also highlights areas where future clinical research could be directed to address unresolved hypotheses in alopecia areata patient care.
Authors: Dmitri Wall; Raed Alhusayen; Bernd Arents; Christian Apfelbacher; Esther A Balogh; Laita Bokhari; Manja Bloem; Angela L Bosma; Tim Burton; Leslie Castelo-Soccio; Nicole Fagan; Steven R Feldman; Godfrey Fletcher; Carsten Flohr; Esther Freeman; Lars E French; Christopher E M Griffiths; George J Hruza; John R Ingram; Michael D Kappelman; Irene Lara-Corrales; Henry W Lim; Nekma Meah; Devon E McMahon; Satveer K Mahil; Ian McNicoll; Annelie Musters; Haley B Naik; Rodney Sinclair; Catherine H Smith; Phyllis Spuls; Desmond J Tobin; Katherine York; Alan D Irvine Journal: Clin Dermatol Date: 2021-04-06 Impact factor: 3.541
Authors: Brett A King; Maryanne M Senna; Manabu Ohyama; Antonella Tosti; Rodney D Sinclair; Susan Ball; Justin M Ko; Marc Glashofer; Rodrigo Pirmez; Jerry Shapiro Journal: Dermatol Ther (Heidelb) Date: 2022-03-31